Prognostic implications of ischemia modified albumin in known cases of86 elderly hypertensive South Asian aged 56-64 years - a hospital based study
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2014, Vol 4, Issue 0
Abstract
Objective: To study associated ischemia modified albumin in hypertensive participants and to compare the results with normotensive healthy controls. Methods: A total of 86 hypertensive patients and 86 age-sex matched normotensive healthy volunteers were selected for this study. The study was conducted for a period of 3 years from September 2007 to August 2010. Biochemical parameters and other parameters such as smoking habits, systolic and diastolic blood pressure and family history were recorded. Lipid profile, ischemia modified albumin, malondialdehyde and conjugated diene were measured by standard methods and results were compared between patients and controls. Results: Total cholesterol, triglycerides, low density lipoprotein cholesterol were significantly higher (P<0.001 ) in hypertensive subjects when compared to normotensive control. Also, significant differences were seen in high density lipoprotein cholesterol levels between both groups (P<0.001 ). The index of lipid per oxidation comprising both malondialdehyde and conjugated dienes were significantly higher in hypertensive compared to normotensive controls. Ischemia modified albumin levels were significantly increased among hypertensive compared to normotensive controls (P<0.001). Conclusions: Hypertensive patients have increased oxidative stress and are accompanied with rise in ischemia modified albumin. Ischemia modified albumin could be incorporated as a diagnostic test parameter in hypertensive to avoid the future acute coronary complications.
Absolute lymphocyte count as a surrogate marker for CD4+ cell count in monitoring of antiretroviral therapy, Northwest Ethiopia: retrospective evaluation
Objective: To determine the use of total lymphocyte count as a surrogate marker for CD4+ cell count among HIV infected patients at the University of Gondar Hospital. Methods: A retrospective cross sectional study was con...
Completeness of malaria notification in Tunisia assessed by capture recapture method
Objective: To estimate the completeness of malaria notification to the public healthcare system (PHCS) and to describe retrospectively data of malaria cases in Tunisia. Methods: We conducted a retrospective epidemiologic...
Effect of embelin on lithium-induced nephrogenic diabetes insipidus in albino rats
Objective: To evaluate the nephroprotective and anti-polyuric role of embelin on lithium induced nephrogenic diabetes insipidus (NDI) in albino rats. Methods: NDI induced by lithium chloride (4 meq/kg/day, i.p. for 6 day...
Epidemiological patterns of Leptospira spp. among slaughterhouse workers in Zanjan- Iran
Objective: To determine epidemiological patterns of Leptospira spp. among slaughterhouse workers in Zanjan- Iran during 201 1. Methods: 98 human blood samples collected from slaughterhouse workers in Zanjan province, in...
Anti-obesity and hypoglycemic effect of ethanolic extract of Murraya koenigii (L) leaves in high fatty diet rats
Objective: To evaluate the hypoglycemic and anti-obesity activities of of Murraya koenigii leaves. Method: The study was performed in high fatty diet induced obesity rats. After 15 days baseline period the treatments ani...