Prognostic score of hyperlactatemia under ART
Journal Title: Terapeutica, Farmacologie si Toxicologie Clinica - Year 2008, Vol 12, Issue 1
Abstract
Background: mitochondrial toxicity is an adverse event of nucleoside reverstranscriptase inhibitors. The biochemical marker is the increased level of serum lactate. Objectives: to identify the risk factors for hyperlactatemia and to establish a prognostic score. Methods: we prospectively studied 49 adults under ART. Lactate level and other parameters were studied. Univariate and multivariate statistics were used. Results: risk factors for hyperlactatemia are: age over 40 and hemoglobin under 11g%. The result of prognostic score was 0.5. Conclusions: a good prognosis means a score under 0.5. The score might be a replacement method for the lactate concentration
Authors and Affiliations
Corina Itu, C. Jianu, Doina Ţăţulescu, Mirela Flonta, Ligia Ursu, Virginia Zanc, D. Cârstina
Keywords
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