Progress research on non-drug therapy in cancer-related fatigue
Journal Title: TMR Non-Drug Therapy - Year 2020, Vol 3, Issue 4
Abstract
Highlights This article reviews the progress research on non-drug therapy in cancer-related fatigue, including exercise intervention, psychological intervention, sleep intervention, nutrition intervention, bright white light therapy, etc., to provide an evidence-based guideline for clinician. Abstract Cancer-related fatigue is the most prevalent and persistently symptom in cancer survivors than any other symptom, which is caused by both the disease and its treatment. Patients with cancer show a severe symptom of fatigue, which cannot be relieved by general rest or sleep. Cancer-related fatigue negatively impacts a patient's physical and emotional function, social ability and even patients’ prognosis. At present, the mechanism of cancer-related fatigue remain unclear despite much research, and a variety of mechanisms may contribute to its occurrence and development, including inflammatory reaction, metabolism dysregulation, immune activation, hormonal changes, central nervous system dysfunction, etc. Now a broad variety of drugs and non-drugs interventions are used against cancer-related fatigue. The intervention of conventional western medicine mainly contains hematopoietic stimulants, hormones, mental stimulants, and antidepressants, but their widely clinical application is limited by their effectiveness and possible side effects to a certain degree. There are also many forms of non-drug interventions for managing cancer-related fatigue, such as exercise intervention, psychological intervention, sleep intervention, nutrition intervention, bright white light therapy, etc. The aim of this review is to provide recommendations of non-drug interventions for patients with CRF during and after cancer treatment, in order to provide an evidence-based guideline for clinicians.
Authors and Affiliations
Kai Zhou1,2 ,Jia-Yu Zhang1 ,Xi-Wei Yang1 ,Da Shen3 ,Jun-Jin Li2 ,Yan-Fang Cheng2 ,Xiao-ling Qian2 ,Pei-Xian Zhang2,4*
Keywords
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- EP ID EP690468
- DOI 10.12032/TMRND20201225020
- Views 131
- Downloads 0
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