PROMETHAZINE AN ENVIRONMENTAL FRIENDLY REAGENT FOR NOVEL ESTIMATION OF HYPOCHLORITE IN ENVIRONMENTAL SAMPLES
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2019, Vol 8, Issue 9
Abstract
A simple, rapid and accurate spectrophotometric method has been developed for the determination of hypochlorite using promethazine. The proposed method reports the reaction of hypochlorite with promethazine in acid medium to form a red colored product with an absorption maximum at 517 nm. Beer’s Law was obeyed in the range of 1-10 μg/ml with molar absorptivity of 0.382×104 L.mol-1.cm-1 and sandell sensitivity 0.0195μg/cm2. The relative standard deviation of the method was less than 2% and accuracy (average recovery) was 100±1.7%. The optimum conditions for all color development are described and the proposed method has been successfully applied for the determination of hypochlorite in drinking tap water and household bleaching samples.
Authors and Affiliations
Nief Rahman Ahmed
Keywords
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- EP ID EP669105
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