Prospective Cross Sectional Study of Incidence and Correlation of Dyslipidemia in Predicting Outcome of Patients Diagnosed with Cerebrovascular Accident
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 6
Abstract
Introduction: Lipid abnormality has been described as one of the risk factor for ischemic stroke. However, there are limited studies comparing stroke pattern (infarction and hemorrhage) with lipid profile of patients. Study aimed to study incidence and correlation of lipid abnormality in cerebrovascular accident (CVA) patients. Material and Methods: Hundred and twenty seven subjects were studied after dividing in to Cases (n=102, with CVA) and Control (n=25, without CVA) in the Department of Medicine G R Medical College and JA Group of Hospitals, Gwalior between April 2015 to August 2016. Detailed history and lipid profile was recorded for each subject. Stroke pattern was analyzed using brain CT/MRI for each patient. Results: Most of the subjects among Cases and Control belong to the age groups of 61-85 years (45.09%) followed by 41-60 years (44%) respectively. Among Cases, maximum patients were males (61.76%) whereas among Control, maximum patients were females (84%). Most of the cases were smokers (53.92%). Among smokers of Case group, infarction (55%) was more common compared to hemorrhage (51%). Dyslipidemia was more common among cases (56.86%) compared to control (28%) (p=0.009). Majority of patients (63.07%) with infarct had dyslipidemia as compared to patients with hemorrhage (45.94%). Decreased high density lipoprotein (HDL) level (74%) was the main culprit among Cases followed by decreased total cholesterol (64%). Out of 14 expired patients in Cases, 71.42% had dyslipidemia. Conclusion: Decreased level of HDL was most commonly reported among ischemic compared to hemorrhagic stroke. Dyslipidemia was most commonly reported in patients who died because of stroke.
Authors and Affiliations
Jagat Pal Singh, Sapna Nagvanshi
Keywords
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