Prospective randomized double blinded comparative study on the effects of ephedrine and phenylephrine on fetal outcome and their effects on hypotension during elective cesarean section
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3
Abstract
Introduction Hemodynamic instability during pregnancy may compromise the blood flow to the uteroplacental bed which may lead fetal acidosis We compared ephedrine and phenylephrine on fetal outcome and hypotension during elective cesarean sectionAim To compare the effectiveness of ephedrine versus phenylephrine in fetal outcome and the treatment of fall in blood pressure during subarachnoid block for elective cesarean sectionMaterials and Methods Study Design Prospective randomized double blindBased on inclusion and exclusion criteria 50 patients were selected and divided into two equal groupsAll patients were done under subarachnoid block as per routine in our hospitalGroup E received Ephedrine 6mg if 20 fall in the heart rate and systolic blood pressure from the baselineGroup P received phenylephrine 20mcg as increments if20 fall in the heart rate and systolic blood pressure from the baselineResults Both the groups were comparable with regard to the fetal outcome Apgar score and fetal umbilical vein ABG Nylephrine group showed statistically significant fall in heart rate and systolic blood pressure when compared to the Ephedrine group during the first 20minutes After 25th minute both the drugs were comparableConclusion Both the drugs were comparable with respect to the fetal outcome and maternal hemodynamics in patients undergoing elective cesarean section under subarachnoid block Keywords Ephedrine Phenylephrine Hypotension Subarachnoid block Cesarean section
Authors and Affiliations
A Pushparani, R Anitha Preethi
Keywords
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- EP ID EP476466
- DOI 10.18231/2394-4994.2018.0062
- Views 67
- Downloads 0
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