Prospective Study of Core Needle Biopsy on Bone Lesion
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2018, Vol 3, Issue 10
Abstract
Bone is the host to many diseases. Diagnostic biopsies of bone lesions are generally done in two forms i.e. Percutaneous core needle biopsy or open surgical biopsy. Core needle biopsy is initial method of tissue diagnosis in bone tumours. To study the adequacy and accuracy of core needle biopsy in diagnosing bone lesions. To establish definitive diagnosis of bone pathology. The study was conducted in department of pathology, MNJ Cancer Institute and TB & Chest hospital, Osmania Medical College, Hyderabad. A total of 53 cases were analyzed prospectively for a period of two years from October 2015 to September 2017. Female to Male ratio was 1.1:1, Average age 3 to 70 years. Out of 53, 26 cases were primary malignant bone tumors, 12 were metastatic deposits, 10 were benign tumours (9 -Giant cell tumors,1-osteo chondroma) 2 were chronic osteomyelitis,3 were not adequate. In 26 cases of primary malignant tumours 10 - osteosarcoma, 6 - ewings sarcoma, 4 - chondrosarcoma, 2 - plasma cell neoplasm, 1 case was high grade NHL, 1 - chordoma, 1 synovial sarcoma,1 germ cell tumour. Adequacy rate (94.6%) in our study is in concordance with the similar study of Amit Joshi et al., (2013) where adequacy rate was 92%.present study is also in concordance with study of Logon et al with adequacy rate of 97.8%. It has demonstrated that the Core needle biopsy is a safe, easy, and effective technique for the evaluation bone tumours, with a high rate of diagnostic yield and accuracy.
Authors and Affiliations
Sandhya Bangaru, Dr. N. Vivekanand, Dr. K. Durga
Vancomycin Resistance in Clinical Isolates of Methicillin Resistant Staphylococcus aureus from a Tertiary Care Hospital
Staphylococcus aureus is one of the most common causes of Blood Stream infections (BSI), skin and wound infections, osteomyelitis, endocarditis, and nosocomial infections, especially pneumonia, surgical site infections (...
Study of Emergence, Prevalence and Sensitivity Pattern of Acinectobacter Spp. in Tertiery Care Hospital Jamnagar, Gujarat, India
Acinetobacter has emerged as significant hospital pathogen involved in outbreaks of hospital infections, notoriously known to acquire antibiotic resistance to most of the commonly prescribed antimicrobials. Many risk fac...
Primary Pure Squamous Cell Carcinoma of Gallbladder Presenting as Chronic Cholecystitis: A Rare Case Report
Abstract:Primary Squamous cell carcinoma of the gallbladder is extremely rare and constitutes 0.5- 3% of all gall bladder malignancies. We report a 50-year-old female who presented with vague symptom of right upper quad...
AStudyofHistopathologicalSpectrumofGastrointestinalEndoscopicBiopsiesinaTertiaryCareCentre
Abstract:Endoscopy with endoscopic biopsy is currently the major method of diagnosis of gastrointestinal (GI) neoplasms. A total of 60 endoscopic biopsy specimens from upper and lower gastrointestinal tract were studied...
Red Cell Distribution Width in Various Clinical Settings and Correlation with Inflammatory Markers and Serum Parameters: A Prospective Study
Red cell distribution width (RDW) is a measure of degree of variation in the red blood cell size. RDW is recorded as a part of the standard complete blood cell count. The objective of this prospective research study is...