Prostaglandin E2 (PGE2) Level in the Gingival Crevicular Fluid (GCF) Of Sudanese Patient with Chronic Periodontitis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background: The purpose of the present study was to evaluate the level of prostaglandin E2 in gingival Crevicular fluid of patients with chronic periodontitis. Material and Methods: Thirty patients diagnosed with chronic periodontitis in the periodontal department in Khartoum Dental Teaching Hospital and sixty controls were enrolled in the study. GCF was collected using paper strips (periostrip) inserted into the gingival sulcus for 30 seconds then put in a cryoviale tube in frozen media and sent to the lab. Clinical examination is carried out using dental mirror and William's graduated periodontal probe. Plaque index (PI), gingival index (GI), periodontal pocket depth (PPD), Recession (R), clinical attachment loss (CAL), was recorded in the data sheets. Results: Thirty case and sixty controls from both genders with age range 25-45 years were included in the study. The results showed that highest mean concentrations of PGE2 in GCF were obtained from the study group; while the lowest concentrations were obtained from the control subjects with p value 0.001(statistically significant). There was a relationship between the mean PGE2 concentration in GCF and mean of the clinical parameters (PI, GI, PPD, R, CAL) with p value 0.009(statistically significant). Conclusion: There was strong association between the PGE2 in GCF levels and severity of chronic periodontitis
Authors and Affiliations
Safinaz Hussien, Ibrahim Ahmed Ghandour
Keywords
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- EP ID EP256063
- DOI 10.9790/0853-1609053646
- Views 77
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