Protein S100A8/A9: A Potential New Biomarker for Pancreatic Diseases
Journal Title: International Journal of Clinical Endocrinology and Metabolism - Year 2017, Vol 3, Issue 1
Abstract
Objectives: S100A8/A9 expression has been linked to carcinogenesis and inflammation. We hypothesized that S100A8/A9 protein serum levels are a useful stratification marker for patients with pancreatic ductal adenocarcinoma (PDAC), intraductal papillary mucinous neoplasm (IPMN) or chronic pancreatitis (CP). Methods: S100A8/A9 serum levels were analysed in PDAC, CP and IPMN patients and compared to S100A8/A9 healthy donor controls (HD) using ELISA. S100A8/A9 levels and clinical data were statistically analysed.
Authors and Affiliations
El Gammal Alexander T, Sturm Jörn H, Pinnschmidt Hans O, Hofmann Bianca T, Bellon Eugen, Ghadban Tarik, Melling Nathaniel, Bachmann Kai, Izbicki Jakob R, Bockhorn Maximilian, Güngör Cenap, Perez Daniel R
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