Proteomic studies in pregnant and lactating cows. A review
Journal Title: Journal of Animal and Feed Sciences - Year 2014, Vol 23, Issue 3
Abstract
Proteomics, an innovative branch of science, deals with comprehensive analysis of protein expression at a particular time in a given biological system. Proteomics enables analysis of the repertoire of proteins, comparison of protein profiles, and reveals changes in expression. Proteomic studies may be useful in solving scientific problems and may have applications in practice. The use of proteomic techniques is increasing in relation to farm animals in order to assess their health status, growth rate and productivity, but it is worth emphasizing that still is inadequate to needs. The detection of biomarkers enables early diagnosis, prevention, and finding therapeutic solutions. During puberty in heifers and during the first pregnancy and lactation, dynamic and gradual adaptive changes in the intensity of metabolic processes and changes in the activity of regulatory mechanisms are observed. These changes are associated with the growth and development of the foetus, preparation of the mammary glands for lactation, and, after parturition, with reproductive system regeneration and preparation for new fertilization and pregnancy. Comparison of protein profiles and identification of differentially expressed proteins involved in particular metabolic pathways may be useful in comprehensive analysis of functional changes in pregnant and lactating cows. Current knowledge, results of scientific studies, and their application into practice indicate that proteomics will introduce new standards into physiological research in the near future. This paper presents studies on pregnant and lactating cows, with emphasis on proteomics of blood serum/ plasma, foetal membranes, liver, amniotic fluid, allantoic fluid, uterine fluid, urine, mammary gland, milk, and comparative proteomics of healthy and sick cows.
Authors and Affiliations
A. Kurpińska, W. F. Skrzypczak
Keywords
Related Articles
- EP ID EP75682
- DOI -
- Views 74
- Downloads 0
Influence of different levels of dried citrus pulp on in vitro ruminal fermentation kinetics of total mixed ration in goat rumen inocula
30% (DCP30) of the total mixed ration (TMR) was evaluated by in vitro gas production (GP), and ruminal fermentation patterns, in a completely randomized design. Rumen fluid was collected before the morning meal from 8 ge...
Responses of Nili-Ravi buffalo to aflatoxin B1 with and without toxin adsorbents
The objective of the study was to determine the responses of Nili-Ravi buffalo to aflatoxin B1 (AFB1) in terms of feed intake, haematological and serum biochemical parameters and to compare the efficacy of three differen...
The dietary level of selenite and selenized yeast influences the concentrations of selected fatty acids in the abdominal fat and brain of rats
The effects of supplementing diets with a mixture of conjugated linoleic acid (CLA) isomers (CLAmix) and/or selenium as Na2 SeO3 (SeIV) or selenized yeast (SeY) on the growth performance of rats and on the contents of s...
The effect of a dietary herbal extract blend on the performance of broilers challenged with Eimeria oocysts
The effect of a dietary herbal extract blend on the performance of broilers challenged with Eimeria oocysts
Effects of dietary phytic acid on digestibility of main nutrients and mineral absorption in mink (Mustela vison)
The objective of the study was to evaluate the effects of dietary phytic acid (IP6) on the apparent total tract digestibility (ATTD) of main nutrients and apparent absorption of minerals in mink (Mustela vison). A basal...