Proton pump inhibitors may improve glycemic control in patients with Type 2 DM- A prospective cohort study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
The study objectives were to determine the effect of proton pump inhibitors on glycemic control in patients with Type 2 DM by measuring the parameters like FBS, PPBS and HbA1C. A Prospective Cohort study was conducted in 80 patients at General Medicine Department of RIMS, Kadapa. Then, these patients were divided into two group’s i.e., for one group, oral hypoglycemic agents along with proton pump inhibitors were prescribed and for the second group, only oral hypoglycemic agents were given. Both the groups were followed for two months and FBS, PPBS and HbA1C were measured. This procedure repeated with the new study population for the second and third two months, as the study is for about six months. The present study shows the incidence for type 2 DM is 0.017, and the prevalence is 0.06. Out of 80 study population, average base line FBS for patients with PPI (40 patients) was 177.235 and average baseline FBS for patients without PPI (40 patients) was 176. And average FBS in follow up for the patients with and without PPI was 149.425, 156.025 respectively. Out of 80 study population, average base line PPBS for patients with PPI (40 patients) was 254.125and average baseline PPBS for patients without PPI (40 patients) was 265.5. And average PPBS in follow up for the patients with and without PPI was 216.275, 240.25 respectively. Our results suggest a role for PPI as an adjunctive therapy for DM and glucose-insulin homeostasis and better glycemic control.
Authors and Affiliations
Dr. Madhan Mohan Rao, Dr. S. Parveen, S. Deva sree, K. Bhargavi, Ch. Ascharya, A. V. Kavya sree, V. Harika
Keywords
Related Articles
- EP ID EP467596
- DOI 10.9790/0853-1802106773.
- Views 45
- Downloads 0
A Case Of Adolescent Chronic Calcific Non Alcoholic pancreatitis And Autosomal Dominant Polycystic Kidney Disease
Tropical chronic pancreatitis (TCP) is a type of chronic calcific non alcoholic pancreatitis mainly occurs in tropical countries.Younger age at onset ,intraductal calculi , intractable course of the disease and developme...
Measurement of Obstetrical Conjugate Diameter by USG and its association with mode of Delivery.
Pelvic assessment done by measuring the Obstetrical Conjugate Diameter by transabdominal Ultrasonography at term can provide additional information for assessing the Maternal Pelvis to the clinician and may be helpful in...
Is Dengue Epidemic Masking The Incidence Of Scrub Typhus? An Observational Study
Srub typhus, an acute febrile illness caused by Orientia tsutsugamushi, is essentially a vasculitic disorder which if left untreated or improperly treated can lead to serious end organ damage and death. So its early diag...
Efficacy of Intracuff Alkalinized 2% Lidocaine in Reducing Cough, Sore Throat And Hoarseness During Emergence in Smokers Undergoing Laparoscopic Surgery
Background: Cough causes various complications during emergence from general anaesthesia especially in smokers. Objective of the Study: To assess the efficacy of intracuff alkalinized 2% lidocaine as compared to saline i...
Hepatitis B Virus DNA in Sera of Apparently Healthy Carriers Blood Donors with Anti-Hbc Total Positive
Objective this study was attempt to molecular estimation of Hepatitis-B Virus DNA (HBV-DNA) in sera of apparently healthy carriers blood donors with anti-HBc Total positive alone and discussed the reasons that lead to di...