Przyśpieszona pooperacyjna radioterapia u chorych na zaawansowanego raka krtani

Journal Title: Otolaryngologia Polska - Year 2010, Vol 64, Issue 7

Abstract

Aim: The aim of study was test effi cacy of accelerated postoperative radiotherapy – concomitant boost in patients with advanced larynx cancer. Methods and Materials: The prospective study included 112 patients with advanced larynx cancer after radical surgical treatment. Patients had postoperative radiation therapy, conventional (C) or accelerated (CB). Results: The 3-year overall survival in CB was 59%, in C – 58% (p=0,2), 3-year locoregional control in CB – 83%, in C – 75% (p=0.01), the 3-year disease free survival was in CB – 72%, C – 66% (p=0.1). Conclusion: Concomitant boost postoperative radition therapy did not improove overall survival, loco-regional control, disease free survival. Patients with close surgical margins, longer interval between surgery and radiation, high level of hemoglobin, T4 had benefi t from accelerated radiotherapy.<br/><br/>

Authors and Affiliations

Jadwiga Kubrak, Maria Chosia, Piotr Maj, Alina Jarema

Keywords

Related Articles

Expression of Toll-like receptors on peripheral blood white cells in acute otitis media

Objective: From 10 to 15% of children suffer from recurrent acute otitis media (AOM). An association between polymorphism in TLRs and their co-receptor CD14 with otitis media proneness has been described in children.More...

Przydatność badania ruchomości okienka okrągłego za pomocą Laser Doppler Vibrometer w ocenie rekonstrukcji łańcucha kosteczek słuchowych w tympanoplastykach typu zamkniętego

Round window’s movability measurements with helping of LDV in evaluation of ossicular chain functioning. Aim of study: Quantitive evaluation of round window movability in normal conditions and after malleus stapes assemb...

Schemat postępowania i wstępne wyniki leczenia brodawczaków krtani dotkankowym preparatem cidofovir

Introduction: Recurrent respiratory papillomatosis (RRP) is a rare disease in children and adults. It is characterized by proliferation of benign squamous cell papillomas within the respiratory-digestive tract, predomina...

GJB2 sequencing in deaf and profound sensorineural hearing loss children

Introduction. GJB2 mutations are the most frequent reason of genetic congenital hearing loss. The aim of the study was to assess the prevalence of GJB2 mutations in the deaf and profound hearing loss children.Material an...

Biofilm from patients with chronic rhinosinusitis. Morphological SEM studies

Introduction. Bacterial biofilm is a three-dimensional structure made of aggregates of bacterial cells (microcolonies) and the extra cellular matrix released by them, adhering to organic and inorganic surfaces. It is est...

Download PDF file
  • EP ID EP345879
  • DOI -
  • Views 84
  • Downloads 0

How To Cite

Jadwiga Kubrak, Maria Chosia, Piotr Maj, Alina Jarema (2010). Przyśpieszona pooperacyjna radioterapia u chorych na zaawansowanego raka krtani. Otolaryngologia Polska, 64(7), 60-64. https://europub.co.uk/articles/-A-345879