Psoriatic Manifestation on a Healed Herpes Zoster Lesion: A Case of Koebner Phenomenon Resistant to TNF-α Inhibitors
Journal Title: Journal of Clinical Immunology & Microbiology - Year 2021, Vol 2, Issue 1
Abstract
Herpes Zoster (HZ) and psoriasis are common cutaneous diseases and in some patients psoriatic manifestations may appear over healed HZ lesions. This manifestation has been defined as Koebner Phenomenon (KP) or Wolf Isotopic Phenomenon (IP). We report a 35-year-old man with chronic moderate plaque psoriasis who developed KP at the areas of healed HZ. We noticed a lack of response to TNF alfa inhibitor treatment in the lesions previously affected by HZ. Therefore, we assume that other inflammatory mediators, in particular Substance P, can be related to the psoriatic manifestations over healed HZ lesions.
Authors and Affiliations
Capalbo Alessandro, Gagliostro Nazareno, Balampanos Charalampos Georgios, Bushati Vilma, Persechino Flavia, Giordano Domenico, Persechino Severino*
Keywords
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- EP ID EP699091
- DOI http://dx.doi.org/10.46889/JCIM.2021.2105
- Views 93
- Downloads 0
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