QUANTITATIVE ANALYSIS OF VALERENIC ACID IN HERBAL PRODUCTS ON BOSNIAN MARKET USING HPLC METHOD
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 5
Abstract
Valerian (Valeriana officinalis L.) has been used in traditional medicine as a mild sedative and sleep-promoting agent. Sesquiterpenic acids expressed as valerenic acid consist of three fractions valerenic acid, cetoxyvalerenic acid and hydroxyvalerenic acid. These characteristic components of valerian are used as analytical markers to evaluate the quality of valerian preparations. Ten different valerian herbal products, in form of tincture, drops, capsules and film coated tablets available on the market have been tested on content of valerenic acids as analytical marker using high performance liquid chromatography (HPLC) method described in Valerian monographs of European Pharmacopoeia and United States Pharmacopoeia (USP).
Authors and Affiliations
Maja Pašić- Kulenović
Keywords
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