Radiological Abnormalities in HIV Infected Patients with Neurologic Symptoms and Diagnostic Accuracy of CT and MRI Scans of Brain
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Introduction: Prevalence of HIV infection is high in India with neurological complications developing in many patients. CT scan and MRI are helpful in identifying the neurological abnormalities in such patients. This study aims to find prevalence of various neurological abnormalities in HIV infected patients with clinical evidence of neurological involvement in a tertiary care center and to assess the accuracy of CT scan and MRI in their evaluation. Materials and Methods: This was a cross sectional observational study done in Department of Radiodiagnosis, for one year and six months. HIV positive patients having neurological symptoms referred for CT scan or MRI scan of brain were included. CT scan was taken for 54 patients and MRI for 48 patients. Presumed diagnosis was made from radiological diagnosis, history, clinical and laboratory data, based on which the patients were treated. Patients were then followed up for final diagnosis made from medical records, based on history, neurological examination, further imaging, laboratory data and treatment response. We correlated the radiological diagnosis from CT scan and MRI with the final diagnosis. Sensitivity, specificity, positive predictive value and negative predictive value for CT scan and MRI were calculated. Results & Conclusion: HIV encephalopathy (n=8), toxoplasmosis (n=6), infarcts and tuberculosis (n=5 each) accounted for most neurological abnormalities. MRI was much more sensitive and specific than CT scan. CT scan could predict final diagnosis in 38 out of 54 cases (70.37% sensitivity) while MRI could predict final diagnosis in 43 out of 48 patients (89.58% sensitivity)
Authors and Affiliations
Ajith MS
Keywords
Related Articles
- EP ID EP281967
- DOI -
- Views 51
- Downloads 0
Histopathological Audit of Gastric Tumours with Special Reference to Expression of MUC2 in Gastric Carcinomas – A Six Month Analysis in a Tertiary Care Centre
Objective: The study is the histopathological audit of Gastric tumours in the Department of Pathology of RG Kar Medical college in six months, with special reference to MUC2 expression in gastric carcinomas. Materials an...
Ectopic Gall Bladder Associated With Segmental Hypoplasia of Right Lobe of Liver: Two Cases
The gallbladder is a pear shaped organ lying in the inferior margin of liver, between the right and left lobes. Its primary function is to store and concentrate bile produced by the liver. The gallbladder is affected by...
Mortality Pattern among Hospitalized Children (29 Days to 12 Years) At a Tertiary Care Hospital in South India
Introduction: Mortality of children is the prime indicator of country’s health status and its development. Understanding the child mortality among different age groups is one of the valuable public health insights. There...
Lymph Node Staging in Patients of Head & Neck Malignancies with Clinically Negative Neck Examinations by Ultrasound and Ultrasound Guided Aspiration Cytology
Head and neck cancer is very common with incidence rates varying from 10-15% in various sociodemographic regions and approximately 50% of all malignant tumours in males in India. More than 90% of head neck cancers are sq...
A Study on Complications of Supracondylar Fractures of Humerus in Children
Background: Supracondylar fracture of the humerus is a common elbow injury in children. The main objective of this study was to determine the epidemiological characteristics and complications supracondylar fractures of t...