RAISED DOSAGE OF CASHEW LEAVES EXTRACT (ANACARDIUM OCCIDENTALE) MORE POTENT THAN OMEPRAZOLE IN GASTRIC SECRETION ULCER TREATMENT
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 6
Abstract
Effects of ethanolic extract of cashew leaves in thirty six (36) male and female albino rats with induced gastric ulcer were investigated for 14 days. The animals were divided into six (6) groups with six animals in each group. Group I served as control without gastric ulcer. Group II –V with gastric ulcer were administered with various concentrations while group VI group had omeparazole treatment. The mean gastric ulcer count in group II and III was significantly (P<0.05) higher than that of control. Group VI had higher ulcer counts than control but lower counts significantly (P<0.05) as compared to group II and III. Group V ulcer counts were not different significantly with control but were lower significantly (P>0.05) compared with group II, III and IV. The gastric secretion in group II was not different significantly (P>0.05) compared to control group, on day 7, increased in group III (P<0.05) and on day 14 compared to control. The gastric secretion in group IV was not significantly different (P>0.05) as compared to control on day 7, but increased significantly (P<0.05) on day 14 compared to control Group V with high dose of extract had low gastric acid secretion on day 7 not significantly different (P>0.05) as compared to control and higher significantly on day 14. Group VI with omeprazole treatment had lower gastric secretion significantly different (P<0.05) compared to control in day 7 but higher secretion significantly different from that of control on day 14. It was observed that at high dose of the extract low ulcer count and low gastric secretion were recorded compared with the orthodox drug, omeprazole. It is affirmed that cashew leaves extract is a potent antiulcerogenic therapy.
Authors and Affiliations
Dr. Jimmy E.
Keywords
Related Articles
- EP ID EP628676
- DOI -
- Views 163
- Downloads 0
CONCEPT OF INDUCTION OF NORMAL LABOR THROUGH AYURVEDA
In the present day scenario, incidence of operative interference in labor is increasing due to many causes like delayed conception, lack of pain threshold and high risk pregnancies. As the process of child birth is a nat...
PRESENCE OF SEROTONERGIC 5HT4-TYPE RECEPTORS IN BROILER’S SMALL INTESTINE
The aim of the present study was to try to determine the possible distribution of 5-HT4 receptors in small intestine of broilers (duodenum, jejunum and ileum). The disturbances of bowel function are common in broilers an...
ANALYSIS ON CHEMICAL COMPONENTS OF XINYI VOLATILE OILS OF YULANIA AXILLIFLORA DIFFERENT SPECIES
Xinyi, flower bud of Yulania (Spach) plants, is a kind of traditional chinese herbal medicine for treating rhinitis. To investigate the effect of species on chemical components and curative effect of Xinyi, hydrodistille...
FORMULATION AND EVALUATION OF CANDESARTAN CO-PRECIPITATE WITH HYDROPHILIC POLYMERS; PREPARATION OF ORODISPERSIBLE TABLETS
Candesartan cilexetil is an angiotensin-receptor blocker that suffer from inadequit and variable oral bioavailability due to its poor aqueous solubility and presystemic metabolism. Therefore, the objectives of this study...
ANTICANDIDAL ACTIVITY OF ETHANOLIC EXTRACT OF CLOVE AGAINST CLINICAL ISOLATES OF CANDIDA
The incidence of both community acquired and hospital acquired mycotic infections has significantly elevated since past few decades, in accounts of growing number of high risk patients, those with impaired immunity.[1] O...