Rapid Identification of Clinically Important Aerobic Microorganisms by Automated Blood Culture System and their Antimicrobial Resistance Pattern at Tertiary Care Hospital at Western Rajasthan India
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
The rapid identification of clinically important microorganisms from positive blood culture provides important diagnostic and therapeutic information. Blood stream infections can lead to life threatening sepsis, require rapid diagnosis and rapid antimicrobial treatment. Aim of our study was isolation and identification of aerobic pathogens causing bacteremia & septicemias and their antibiotic resistance patterns in a tertiary care hospital western Rajasthan. 628 blood samples collected from clinically suspected cases of bacteremia and septicemias were studied by (BacT/ALERT) automated blood culture system. The isolates were identified by standard phenotypic methods and antimicrobial resistance patterns were determined by CLSI guidelines. Positive blood cultures were obtained in 182 (28.9%) of cases. Among gram positive Staph aureus (39.5%) whereas gram negative Klebsiella (16.48%) were predominant isolates, and 3.8% were Candida species. Among staph aureus methicilin among klebsiella cefixime and among pseudomonas ticarcilline was the most resistance drug. The prevalence of MRSA,VRSA and VRE were 86.1%, 9.7% and 50% respectively. Overall high positive rates of blood culture were observed. Rapid isolation of pathogens by automated blood culture system provide early and appropriate treatment to seriously ill patients leading to reduce mortality and duration of hospital stay
Authors and Affiliations
Dr. R. S. Parihar
Keywords
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