Rapid progressive dementia and involuntary movement caused by vitamin B12 deficiency: a case report
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 3
Abstract
A 41-year-old male was presented with rapidly progression memory impairment for 2 months and episodic limb shaking for 2 weeks as the main manifestations. Physical examination showed verbal disadvantage with decreased memory, attention, comprehension, and orientation. Serum vitamin B12 levels decreased, serum anti gastric parietal cell antibodies and anti-intrinsic factor antibodies were positive. Blood analysis showed macrocytic anemia, neuropsychological scale showed functional impairment in multiple cognitive domains, electrophysiological examination showed peripheral nerve damage, cerebrospinal fluid and imaging examination showed no abnormalities. The patient was diagnosed as having vitamin B12 deficiency dementia, vitamin B12 deficiency related involuntary movement and pernicious anemia. Supplementing with B vitamins and folic acid significantly improved cognitive impairment and eliminated symptoms of limb shaking. The purpose of this case report is to enhance the understanding of clinical doctors about dementia and involunting movement caused by vitamin B12 deficiency, in order to diagnose and treat it early.
Authors and Affiliations
Lanlan LIU, Xin JIANG, Xuewei XING, Yanqing TIE, Guosong QI, Jingjing WANG, Xiaoxiao FENG, Peiyuan. LYU
Keywords
Related Articles
- EP ID EP750446
- DOI 10.3969/j.issn.1002-0152.2024.03.009
- Views 23
- Downloads 0
Clinical characteristics of 30 patients with intracranial hypotension syndrome
[Objective] To analyze and summarize the clinical presentation of spontaneous and secondary intracranial hypotension syndrome(IHS). [Methods] Patients diagnosed with spontaneous or secondary IHS from September 2022 to Ma...
Research progress of transcranial alternating current stimulation in the treatment of cognitive impairment in neuropsychiatric diseases
Cognitive dysfunction is the impairment of higher brain functions. Cognitive impairment caused by neuropsychiatric diseases has caused serious impact on patients' quality of life and the outcome of the disease. The trans...
A case report of type II citrullinemia in an adult with epileptic seizure onset
A retrospective analysis was performed on one case of adult-onset type â…¡citrullinemia (CTLN2) caused by homozygous mutations of SLC25A13 genes. The patient, a 28-year-old male, had repeated limb convulsions for more than...
Mid-to-long-term quality of life and psychological status after endovascular embolization of unruptured intracranial aneurysms
[Objective] To investigate whether embolization surgery can improve mid-to-long-term outcomes related to quality of life, anxiety and depression in patients with unruptured intracranial aneurysms (UIA). [Methods] This pr...
Effect of low-frequency repetitive transcranial magnetic stimulation on autism-like behavior in BTBR T+ Itpr3tf/J mice
[Objective] To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) on the BTBR mice, one of the idiopathic autism spectrum disorder mouse models. [Method] Male BTBR and B6 mice wer...