Rare biliary cystic tumors: a case series of biliary cystadenomas and cystadenocarcinoma
Journal Title: Annals of Hepatology - Year 2016, Vol 15, Issue 3
Abstract
Cystic lesions of the liver are common and a major proportion is formed by parasitic cysts and simple cysts. Biliary cystic tumors(BCTs), namely biliary cystadenoma (BCA) and biliary cystadenocarcinoma (BCAC), are rare tumors which usually arise from the intrahepatic biliary tree. BCAs have malignant potential and are difficult to differentiate from BCAC pre-operatively on radiological imaging. Here we have presented 4 patients with BCTs and reviewed the literature pertaining to them.The data of four patients with BCA/BCAC diagnosed and treated at our institute were retrieved from our database and records were reviewed for age, sex, history, imaging, surgery, pathology and follow-up. Mean age of the patients was 53.5 years (range 30-71 years). Two male and two female patients presented with abdominal pain, of which one male patient had pancreatitis at diagnosis. Characteristic features were seen on pre-operative imaging (cystic lesions with internal septations) and biliary communication was identified in the patient with pancreatitis.Three patients were diagnosed with a BCA on final histology, while one patient had a BCAC. Following surgical resection, allthe patients are asymptomatic and disease free with a mean follow-up of 24 months (range 10-40 months). In conclusion, BCTsshould be suspected in the presence of a well-encapsulated, cystic hepatic lesion with internal septations. Although pre-operative distinction between BCA and BCAC is difficult, the lesion, whenever possible, should be completely resected as long-term outcomes are good, especially with BCA.
Authors and Affiliations
Abhirup Banerjee, Sudeep Shah, Abhiyutthan Singh, Anand Joshi, Devendra Desai
Role of nonalcoholic fatty liver disease in hepatocellular carcinoma
Obesity and related disorders are a common cause of morbidity worldwide. Nonalcoholic fatty liver disease is the most important hepatic consequence of adipose accumulation. There is strong evidence of obesity-related dis...
Genetic factors affecting susceptibility to alcoholic liver disease in an Indian population
Introduction. Indians are more likely to develop alcoholic cirrhosis compared to Caucasians, though the cause remains obscure. North Indians tend to consume more alcohol than other parts of the country. Genetic factors a...
Stem cell and hepatocyte proliferation in hepatitis C cirrhosis and hepatocellular carcinoma: transplant implications
Background. The liver possesses two distinct mechanisms for healing. Wound healing via hepatic stem cells recapitulates early development (hepatoblast proliferation), while liver regeneration resembles late embryonic gro...
Recreational physical activity is inversely associated with asymptomatic gallstones in adult Mexican women
Background and rationale. Epidemiologic research suggests that physical activity (PA) reduces the risk of chronic diseases including gallstones. Objective. This study explores the association between recreational physica...
Circulating levels of pentraxin-3 (PTX3) in patients with liver cirrhosis
Background: Despite the circulating levels of PTX3 were related to the severity of various diseases, there are no studies investigating its role in patients with liver cirrhosis. We aimed to study PTX3 levels in patients...