Recent Advances in Fibro-blast Growth Factor-23 Functions
Journal Title: Nephrology – Open Journal - Year 2016, Vol 1, Issue 3
Abstract
During the past decade a lot of work has been done to better understand the roles of fibroblast growth factor-23 (FGF-23); a relatively newly discovered endocrine hormone, in multiple organ systems in the body. This review focuses on expressions of FGF-23, coexpressions of α-Klotho and FGF receptors, and FGF-23 mediated end-organ effects in the physiological and pathological conditions. We also discuss the controversial reports regarding α-Klotho-dependent and α-Klotho-independent functions of FGF-23.
Authors and Affiliations
Zhousheng Xiao
Keywords
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- EP ID EP558225
- DOI 10.17140/NPOJ-1-110
- Views 144
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