Recovery and correction of the balance of microbiota of the gastrointestinal tract of rabbits, disabled as resulting from the use of antibiotics
Journal Title: Біоресурси і природокористування [Biological Resources and Nature Management] - Year 2018, Vol 10, Issue 3
Abstract
The formation, preservation and correction of the balance of the microbiota of the gastrointestinal tract is a complex process in which factors of the external and internal environment participate. To solve the above problems, probiotic preparations are used. However, probiotics, which are used for the prevention and treatment of diseases of the gastrointestinal tract of rabbits, include bacteria isolated from various ecological niches. However, probiotic preparations are more effective, if they include representatives of obligate microbiota of the gastrointestinal tract of animals for which the drug is used. In connection with this, the creation of a probiotic preparation based on biologically active representatives of the obligate microbiota of the gastrointestinal tract of these animals remains topical. Goal. To investigate the ability of the strain of Lactobacillus helveticus 13/2 bacteria to restore and correct the balance of the microbiota of the gastrointestinal tract of young rabbits disrupted by the use of antibiotics. Methods. Microbiological and statistical. Results. Restoration of microbiota balance of the gastrointestinal tract of rabbits, impaired due to the introduction of antibiotics began in the first day after addition of the strain Lactobacillus helveticus 13/2 bacterial suspension to drinking water. The bacteria titer was 1 × 108 CFU / ml. The highest observed efficiency of administration of high doses (50 and 100 ml / l) of the bacterial suspension, provided the positive dynamics of obligate (lactic acid bacteria, bifidobacteria, E. coli) and reducing the number of optional microbiota (yeast-like fungi) in experimental animals as compared with the intestine intact.
Authors and Affiliations
Yu. M. Pokhylko, N. O. Kravchenko
Keywords
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- EP ID EP408304
- DOI 10.31548/bio2018.03.003
- Views 81
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