Recurrent respiratory papillomatosis – epidemiology and characteristics of HPV infection in children
Journal Title: Polski Przegląd Otorynolaryngologiczny - Year 2013, Vol 2, Issue 4
Abstract
Recurrent respiratory papillomatosis (RRP) is the most common non -malignant neoplastic respiratory tract disease in children. Main symptoms are relate d to the period s of recurrent growth of multiple exophytic nodules covering the surface of the mucosa interfering with the patency of the airways. The connection between juvenile onset recurrent respiratory papillomatosis (JORRP) and human papill omavirus (HPV) infection is undisputable and clearly confirmed. Actual epidemiological studies display the relationship between the disease in a child and a low socio -economic status of a family, mother's young age, sexual activity of parents measured by the number of sexual partners before a child's birth and clinically obvious HPV infections in mother or father. RRP in children may be mild and self-limiting or aggressive in character, with a poor prognosis. The papillomas may spread throughout the entire respiratory tree, but most often involve the larynx. Recurrent respiratory papillomatosis causes hoarseness (that may progress to aphonia) and upper respiratory obstruction. The chronic curse of the disease always unfavour bly affects the patient's quality of life. Laboratory diagnosis of HPV infections is dependent upon molecular technique s such as DNA hybridization or nucleic acid amplification. Routine application of molecular techniques such as PCR for detection and analysis of HPV s in patients with RRP has diagnostic and prognostic significance.
Authors and Affiliations
Jarosław Szydłowski
Keywords
Related Articles
- EP ID EP51182
- DOI -
- Views 202
- Downloads 0
Treatment of deafness using bone anchored hearing device (BAHD)
People with hearing loss or deafness in the course of chronic middle ear, external or birth defects, which cannot wear conventional hearing aids or not treatable surgery are candidates for the implant to the bone conduct...
Videostrobokymography and phonovibrogram as a new methods for analysis of vocal fold vibration
Myoblastoma is a rare tumor deriving from Schwann cells. It is located mainly in the tongue, skin and subcutaneous tissue, as well as in the bronchi and digestive tract, although it is rarely found in the larynx. It is a...
Metoda fotodynamiczna w diagnostyce i terapii guzów głowy i szyi
The photodynamic phenomenon is based on the effect of tissue and cell fluorescence, which is excited by the light of a specified wavelength. Photodynamic diagnosing – PDD is based on the effect of ultraviolet rays on neo...
Leczenie chirurgiczne torbieli skórzastej grzbietu nosa: rynoplastyka otwarta
Wprowadzenie: Torbiel skórzasta to łagodny guz typu choristoma, będący odmianą potworniaka. Torbiel skórzasta nosa (TSN) jest najczęstszą wrodzoną wadą linii pośrodkowej w obrębie nosa. Rozpoznanie jest zwykle stawiane d...
Vestibular and balance rehabilitation therapy
Vestibular rehabilitation is an important treatment modality in patients with vestibular and balance disorders. The goals of vestibular rehabilitation are enhancing gaze and postural stability, improving vertigo and dail...