Recurrent wheezing in preterm infants: Prevalence and risk factors
Journal Title: Jornal de Pediatria - Year 2019, Vol 95, Issue 6
Abstract
Objective To evaluate the prevalence and risk factors associated with progression to recurrent wheezing in preterm infants. Methods The cross-sectional study was carried out in 2014 and 2015 and analyzed preterm infants born between 2011 and 2012. The search for these children was performed in a university maternity hospital and a Special Immunobiological Reference Center. The evaluation was performed through a questionnaire applied during a telephone interview. Results The study included 445 children aged 39 (18–54) months. In the univariate analysis, the risk factors with the greatest chance of recurrent wheezing were birth weight <1000g, gestational age <28 weeks, living with two or more siblings, food allergy, and atopic dermatitis in the child, as well as food allergy and asthma in the parents. In the multivariate analysis, there was a significant association between recurrent wheezing and gestational age at birth <28 weeks, food allergy and atopic dermatitis in the child, and living with two or more children. Of the 445 analyzed subjects, 194 received passive immunization against the respiratory syncytial virus, and 251 preterm infants were not immunized. There was a difference between the gestational age of these subgroups (p<0.001). The overall prevalence of recurrent wheezing was 27.4% (95% CI: 23.42–31.70), whereas in the children who received passive immunization it was 36.1% (95% CI: 29.55–43.03). Conclusions Personal history of atopy, lower gestational age, and living with two or more children had a significant association with recurrent wheezing. Children with lower gestational age who received passive immunization against the respiratory syncytial virus had a higher prevalence of recurrent wheezing than the group with higher gestational age.
Authors and Affiliations
Maria Cristina Simões
Keywords
Related Articles
- EP ID EP664352
- DOI 10.1016/j.jped.2018.06.007
- Views 84
- Downloads 0
Efficacy of a public promotion program on children's oral health
Objective To assess the efficacy of the Baby's Mouth early dental care prevention and promotion program in preventing oral diseases (caries, gingivitis, or malocclusions) in children attended since 2010. Methods This wa...
Association between dietary pattern and cardiometabolic risk in children and adolescents: a systematic review
Objective To evaluate the association between dietary patterns and cardiometabolic risk factors in children and adolescents. Data source This article followed the recommendations of PRISMA, which aims to guide review pu...
Body mass index and physical fitness in Brazilian adolescents
Objective Evaluate the relationship between body mass index and physical fitness in a cross-sectional sample of Brazilian youth. Methods Participants were 3849 adolescents (2027 girls) aged 10–17 years. Weight and heigh...
Does height catch-up in schoolchildren have an effect on bone mass in adolescents? Analysis in a Brazilian birth cohort
Objective To analyze the effect of height catch-up at school age on the bone mass of adolescents of a Brazilian birth cohort. Methods A cohort study using data obtained from the three moments (birth, 7/9 years and 18/19...
T-lymphocyte-expressing inflammatory cytokines underlie persistence of proteinuria in children with idiopathic nephrotic syndrome
Objective There is evidence of an important role of immune system changes in the triggering and maintenance of idiopathic nephrotic syndrome (INS). The aim of this study was to investigate the expression of cytokines in...