REDUCED MANGANESE, SELENIUM AND ZINC IN NEWLY DIAGNOSED BREAST CANCER SUBJECTS IN SOUTH WESTERN NIGERIA.
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 2
Abstract
Background: Micronutrients, dyslipidemia and body mass index (BMI) have been established to be risk factors for breast cancer development. Aim: To determine the influence of breast cancer on serum Manganese (Mn), Selenium (Se) and Zinc (Zn) level as well as its association with plasma lipid profile. Materials and Methods: Fasting plasma Total-cholesterol (T-Chol), HDL-cholesterol (HDL-Chol), LDLcholesterol (LDL-Chol), Triglyceride (Tg) and serum Mn, Se and Zn levels were determined in 50 newly diagnosed breast cancer subjects (NDBC) and 50 age matched mammography screened controls, using commercial kits from Randox laboratory and Atomic Absorption Spectrophotometric methods respectively. BMI was calculated using Weight (Kg)/Height (m2 ). Data obtained were subjected to statistical analysis using SPSS statistical package version 17.0.
Authors and Affiliations
Dolapo P. Oparinde
Keywords
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