REDUCED SUSCEPTIBILITY OF MRSA TO VANCOMYCIN
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 9
Abstract
Objective: This study was conducted to observe the antibiogram, vancomycin MIC (Minimum Inhibitory Concentration), and inducible clindamycin resistance in clinical isolates of MRSA (Methicillin-Resistance Staphylococcus aureus).Methods: Drug resistance pattern was studied by Kirby-Bauer disc diffusion methods. MIC of vancomycin was determined by agar dilution method.Results: MRSA was found to be highly resistant to gentamicin (76%), erythromycin (67.03%) and ciprofloxacin (65.09%) while glycopeptides showed uniform susceptibility.Conclusion: Though there was no drug resistance observed against vancomycin and linezolid, it’s wise to use these antibiotics safely as emerging resistance has been reported for these drugs from all over the world.
Authors and Affiliations
Suneel Bhooshan, Jyoti Prasad, Amitesh Dutta, Vandana Ke, Chiranjay Mukhopadhyay
STUDY OF SYNERGISTIC EFFECTS ON ANTIOXIDANT ACTIVITY AND ANTIMICROBIAL ACTIVITY OF POLYHERBAL FORMULATIONS CONTAINING FICUS SPECIES
Objective: The present study aims at screening the synergistic effect on the therapeutic efficiency of traditional herbal medicine Nalpamaradi Choorna and Nalpamaradi Keram, containing four Ficus species. The efficiency...
BIOACTIVITIES OF THE THAI MEDICINAL AND EDIBLE PLANTS C. CAJAN, M. CITRIFOLIA AND O. AMERICANUM
Objective: Inflammation and oxidative stress are closely related and play a role in various diseases. If an infectious component plays a role, an antibacterial effect is of advantage. Thus, natural remedies which combine...
DEVELOPMENT AND VALIDATION OF CARBAMAZEPINE PLASMA CONCENTRATIONS MEASUREMENT AND ITS APPLICATION ON EPILEPSY PATIENTS
Objective: To develop and validate high-performance liquid chromatography with photodiode array (HPLC-PDA) detector as a method for measuring carbamazepine plasma concentrations in epilepsy patients treated with monother...
FIBRINOLYTIC ENZYME FROM BACILLUS AMYLOLIQUEFACIENS: OPTIMISATION AND SCALE UP STUDIES
Objective: This research work was carried out to identify a potent microorganism, which produced the fibrinolytic enzyme and to optimise the media and growth parameters to achieve the maximal enzyme production for commer...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF CURCUMIN AND CYCLOSPORINE BY RP-HPLC
Objective: The present work was undertaken with an aim to develop and validate a rapid reverse-phase high-performance liquid chromatography (RP-HPLC) method for the estimation of curcumin and cyclosporine in the capsule...