REDUCED SUSCEPTIBILITY OF MRSA TO VANCOMYCIN
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 9
Abstract
Objective: This study was conducted to observe the antibiogram, vancomycin MIC (Minimum Inhibitory Concentration), and inducible clindamycin resistance in clinical isolates of MRSA (Methicillin-Resistance Staphylococcus aureus).Methods: Drug resistance pattern was studied by Kirby-Bauer disc diffusion methods. MIC of vancomycin was determined by agar dilution method.Results: MRSA was found to be highly resistant to gentamicin (76%), erythromycin (67.03%) and ciprofloxacin (65.09%) while glycopeptides showed uniform susceptibility.Conclusion: Though there was no drug resistance observed against vancomycin and linezolid, it’s wise to use these antibiotics safely as emerging resistance has been reported for these drugs from all over the world.
Authors and Affiliations
Suneel Bhooshan, Jyoti Prasad, Amitesh Dutta, Vandana Ke, Chiranjay Mukhopadhyay
Keywords
Related Articles
- EP ID EP576058
- DOI 10.22159/ijpps.2016v8i9.13023
- Views 71
- Downloads 0
FORMULATION AND EVALUATION OF SUSTAINED RELEASE DOSAGE FORM USING MODIFIED CASHEW GUM
Objective: The objective of this study was to formulate and evaluate sustained release tablets using cashew gum and cross-linked cashew gum as controlled release polymer.Methods: Full factorial design of 23 was employed...
APPLICATION OFF-LINE SPE-HPLC/UV METHODS IN ANALYSIS OF OFLOXACIN IN HUMAN URINE (IN VITRO)
Objective: The objective of this study is to determine the validity of analytical methods in OFX antibiotic study in human urine (in vitro) using an SPE-HPLC/UV. In this study, SPE was applied in preparing the analysis o...
PRELIMINARY STUDIES ON BRAIN TARGETING OF INTRANASAL ATOMOXETINE LIPOSOMES
Objective: The objective of the present study was to evaluate the enhancement in brain uptake of liposomes containing atomoxetine (ATX-Lipo) for intranasal delivery in the management of Attention Deficit Hyperactivity Di...
NOVEL SMART pH SENSITIVE CHITOSAN GRAFTED ALGINATE HYDROGEL MICROCAPSULES FOR ORAL PROTEIN DELIVERY: II. EVALUATION OF THE SWELLING BEHAVIOR
Objective: The main objective of this study is to evaluate the swelling behavior of pH sensitive chitosan (CS) grafted alginate (ALG) hydrogel microcapsules and compared with a simple alginate-chitosan mixed polyelectrol...
ANTIHYPERLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF CANAVALIA ENSIFORMIS (L) IN HIGH FAT DIET-STREPTOZOTOCIN INDUCED RATS
Objective: It was investigated to enlighten the phytochemical screening and antihyperlipidemic activity of seeds of Canavalia ensiformis (L.) in High fat diet Streptozotocin-induced diabetic rats. Methods: The ethanolic...