Reducing Postoperative Opioid Consumption by Adding Transdermal Fentanyl Patches to Multimodal Analgesia after Breast Cancer Surgery
Journal Title: Journal of Pain & Relief - Year 2018, Vol 7, Issue 4
Abstract
Breast cancer is by far the world's most common cancer among women and in Egypt, it represents 32% of all cancers among females [1,2]. Breast cancer surgeries are associated with moderate-to-severe pain on the first day after surgery (median score of 7 on the Numeric Rating Scale (NRS) [3]. Despite the increased awareness of pain management, postoperative pain is reported by about 80% of surgical patients [4]. Poorly controlled acute postoperative pain may result in a range of detrimental acute and chronic effects (i.e., adverse physiologic responses, delayed long-term recovery and chronic pain) [5]. With good analgesic treatment, pain intensity generally declines from moderate or severe to mild levels after the first 24-48 h after surgery [6]. Multimodal analgesia aims to get optimum effectiveness from the different agents in low dosages in order to minimize side effects from each analgesic. This important concept employs the theory that agents with different mechanisms of analgesia may have synergistic effects in treating acute pain [7]. During postoperative period, strong opioids analgesics may be used for relief of acute pain as it have high efficacy [8]. Intravenous (IV) rout of administration is the most common route used during the early postoperative period. In such cases, a multimodal drugs approach must be employed. This may include the administration of opioids, NSAIDS, and other adjuvant if needed in order to optimize acute pain control in the immediate postoperative period as a bridge till the patient start oral medications [9,10].
Authors and Affiliations
Mohamad MF, Othman AH, Darwish AMM, Elzohry AAM
Keywords
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- EP ID EP578637
- DOI 10.4172/2167-0846.1000326
- Views 62
- Downloads 0
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