Reference values of parathyroid hormone and vitamin D Hormone by chemiluminescent automated assay

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Reference values of parathyroid hormone and vitamin D Hormone by chemiluminescent automated assay

Journal Title: Revista MVZ Cordoba - Year 2015, Vol 20, Issue 2

Abstract

Objective. Provide reference data for parathyroid hormone 1-84 (PTH 1-84) and 25OH Vitamin D (25OH D) using a new technique. Materials and methods. The hormones were evaluated, in serum, using a third generation automated chemiluminescent method for PTH in a group of 60 adult dogs, clinically healthy, grouped according to age in years in GA: 1 to 5, GB: 6 to 10 and GC:>10. Results. Data expressed as average ± DS were for PTH (pg/ml): 9.3±2.3; 12±6.3; 12.2±3.7; and for 25OH D (ng/ml): 84.2±27.8; 68.2±16.0; 63.6±23.1, respectively. The PTH value was significantly greater (p<0.05) in groups B and C in comparison with A, but no significant differences were observed between GB and GC. The 25OH D concentration was significantly less in GB (p<0.05) and in GC (p<0.01) in comparison with GA, showing no differences between GB and GC. A negative correlation between 25OH D and PTH was found (r= -0.28; p=0.015). Conclusions. Data contributed by this study provide reference values for PTH 1-84 and 25OH D, evaluated using a third generation automated chemiluminescent method for PTH in local dogs. The results will facilitate monitoring diseases that alter the metabolism of calcium and phosphorus in dogs.

Authors and Affiliations

Beatriz Martiarena, Esp *| Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Clínica Médica de Pequeños Animales y Hospital Escuela de Medicina Veterinaria,Servicios de Nefrología,Av. Chorroarrín 280, Ciudad Autónoma de Buenos Aires (CP1427) (C.A.B.A.), Argentina.Correspondencia: bmartiar@fvet.uba.ar, Nadia Kogovsek, Bioq| Hospital General de Agudos “Carlos G.Durand” Servicio de Endocrinología, Av. Diaz Velez 5044 (CP 1405DCS) C.A.B.A., Helena Salerni, Esp| Hospital General de Agudos “Carlos G.Durand” Servicio de Endocrinología, Av. Diaz Velez 5044 (CP 1405DCS) C.A.B.A., Víctor Castillo, Ph. D| Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Clínica Médica de Pequeños Animales y Hospital Escuela de Medicina Veterinaria,Endocrinología y,Av. Chorroarrín 280, Ciudad Autónoma de Buenos Aires (CP1427) (C.A.B.A.), Argentina., Georgina Brandi, MV| Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Clínica Médica de Pequeños Animales y Hospital Escuela de Medicina Veterinaria,Laboratorio,Av. Chorroarrín 280, Ciudad Autónoma de Buenos Aires (CP1427) (C.A.B.A.), Argentina., Mariela Regonat, MV| Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Clínica Médica de Pequeños Animales y Hospital Escuela de Medicina Veterinaria,Servicios de Nefrología,Av. Chorroarrín 280, Ciudad Autónoma de Buenos Aires (CP1427) (C.A.B.A.), Argentina., Andrea Visintini, Esp| Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Clínica Médica de Pequeños Animales y Hospital Escuela de Medicina Veterinaria,Servicios de Nefrología,Av. Chorroarrín 280, Ciudad Autónoma de Buenos Aires (CP1427) (C.A.B.A.), Argentina., Héctor Quintana, MV| Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Clínica Médica de Pequeños Animales y Hospital Escuela de Medicina Veterinaria,Nutrición.Av. Chorroarrín 280, Ciudad Autónoma de Buenos Aires (CP1427) (C.A.B.A.), Argentina., P Otero, Bioq| Hospital General de Agudos “Carlos G.Durand” Servicio de Endocrinología, Av. Diaz Velez 5044 (CP 1405DCS) C.A.B.A.

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EP ID EP3403
DOI -
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