Registry Study for Type 2 Diabetes Mellitus in a Diabetic Center in Saudi Arabia with Comparative Analysis for Controlled Versus Uncontrolled Cases

Journal Title: Journal of Endocrinology and Diabetes - Year 2016, Vol 3, Issue 5

Abstract

Background Aims: Comparative analysis of 109 controlled cases versus 120 uncontrolled cases to see the outcome for different treatment methods in type 2 Diabetes Mellitus. Materials and Methods: The study was conducted in a Diabetic Center, included 229 Type 2 Diabetic Patients with mean age of 49.6 ± 12.6 years. 1.7% of patients were on diet only, 69% on oral hypoglycemic drugs, 4.8% on Insulin and 24.5% on combined insulin & oral hypoglycemic drugs. Results: Vitamin D Level increased from 31.3 to 70.3ng/ml and 31.4 to 69.6ng/ml in controlled & uncontrolled patients between beginning & end of the study. Total cholesterol, HDL-C, LDL-C & TG improved by -11.2% & -4.8%, +19.8% & +3.1%, -11.1% & 0.8% and -30.4% & -3.4% in controlled & uncontrolled patients respectively. Hba1c decreased by 15.4% in controlled patients, and by 6.0% in uncontrolled DM patients; (p=0.007). FBG also decreased by 24.9% and 8.1%, for controlled and uncontrolled DM patients. Vitamin D level was investigated in both groups; vitamin D increase (p-value 0.000) has an effect on diabetes mellitus type 2 control. A better lipid profile was seen with controlled patients than uncontrolled patients. Conclusion: Controlled diabetic patients showed better clinical outcomes than uncontrolled patients regarding lipid profile, HbA1c, FBG and Vitamin D deficiency. Strict diabetes control regulates TG and HDL-C, which in turn decreases CV risk.

Authors and Affiliations

Najim Abdulwahid

Keywords

Related Articles

Beneficial Effects of a 1-Year Lifestyle Intervention on Metabolic Abnormalities in Overweight and Obese Schoolchildren in Sousse Tunisia: A Pre-Post Quasi- Experimental Study with Control Group

Introduction: The prevalence of obesity in children has increased worldwide during the most recent decades. In this context, we have conducted this study in the purpose to investigate changes in metabolic syndrome in ove...

Pentraxin 3 as A Cardiovascular Marker in Primary Hyperparathyroidism

Aim: Pentraxin 3 (PTX3) is an acute-phase glycoprotein, which is increased in patients with cardiovascular disease (CVD) and considered as a predictor of CVD in the general population. Accumulating evidence suggests that...

Clinical Variability in Familial X-Linked Hypohidrotic Ectodermal Dysplasia with 2q12Mutation: A Rare Case Report of Female Siblings Agony

Background: Hypohidrotic Ectodermal dysplasia (HED) is a hereditary entity characterized by the abnormal development of embryonic ectodermally derived organs including sweat glands, teeth, and hair. The most prevalent fo...

Increased Neuronal Depolarization Evoked by Autoantibodies in Diabetic Obstructive Sleep Apnea: Role for Inflammatory Protease(s) in Generation of Neurotoxic Immunoglobulin Fragment

Aim Obstructive sleep apnea increases in diabetes and morbid obesity. We tested a hypothesis that circulating autoantibodies in adult type 2 diabetes which increase in association with morbid obesity are capable of causi...

Incidence and Predicting Factors for Abnormal Thyroid Function Test in Adult Patients Post Hematopoietic Stem Cell Transplantation at King Hussein Cancer Center

Introduction: The risk of abnormal thyroid function after hematopoietic stem cell transplantation (HSCT) is well-known especially in pediatric patients. There are few studies about adult patients that showed 3-year cumul...

Download PDF file
  • EP ID EP333695
  • DOI 10.15226/2374-6890/3/5/00165
  • Views 100
  • Downloads 0

How To Cite

Najim Abdulwahid (2016). Registry Study for Type 2 Diabetes Mellitus in a Diabetic Center in Saudi Arabia with Comparative Analysis for Controlled Versus Uncontrolled Cases. Journal of Endocrinology and Diabetes, 3(5), 1-6. https://europub.co.uk/articles/-A-333695