Relationship between ischemia modified albumin and lipid profile in type 2 diabetes mellitus
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction Ischemia modified albumin IMA is new biomarker of oxidative stress and ischemia IMA being increased in Diabetes Mellitus has been described in many studies Diabetes Mellitus DM a metabolic disorder is characterised by hyperglycemia hypertension and hyperlipidemia So our aim was to estimate the levels of IMA in type 2 DM subjects Also to evaluate the relationship of IMA with all the parameters in lipid profile 40TC LDL HDL TG41 in type 2 DM subjectsMaterials and Methods 120 subjects were selected from the medicine OPD of Justice K S Hegde Charitable Hospital Mangalore for study The subjects attending the hospital were from coastal areas of southern India Out of which 60 subjects were type 2 DM patients as per the ADA guidelines and 60 subjects were age and sex matched controls The biochemical parameters estimated were FPS 2hrPG HbA1C Lipid profile 40TC TG LDL VLDL HDL41 and IMA The results were expressed in absorbance units ABSU Data obtained was analyzed using SPSS 20Results The Fasting and postprandial plasma glucose HbA1c serum TG TC LDL HDL IMA were significantly increased in type 2 DM patients than in control subjects with the p value Conclusion The present study suggests that measuring IMA in dyslipidemic diabetic patients will provide an early index of ischemia and its severity This would help in the better management and prognosis of DMKeywords Hyperglycemia Hyperlipidemia Type 2 Diabetes mellitus IMA
Authors and Affiliations
Priya Patil, Shruthi Rai P
Keywords
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- EP ID EP475208
- DOI 10.18231/2394-6377.2018.0100
- Views 60
- Downloads 0
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