Relationship between Obesity and Hypertriglyceridemia on Fatty Liver in Patients at Makassar
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2012, Vol 1, Issue 4
Abstract
Fatty liver is caused by a failure of normal hepatic fat metabolism due to a dysfunction of either within the hepatocytes. The degree of fatty liver is correlating to the increase of body weight. The aim of this study is to investigate any specific relationship between fatty liver and obesity as well as hypertriglyceridemia. This is a cross sectional study by using the retrospective data which is obtained from medical check up at Prodia clinical laboratory during 2006, fatty liver is diagnosed by using ultrasonography, obesity on body mass index (BMI), and triglyceride level by enzymatic colorimetric method.In 204 subjects of medical check up subjects were analyzed. Fatty liver has been found in 67 subjects (32.8%), 95.5% of subjects with obesity, 32.8 subjects with normal triglyceride and 67.2% subjects with hypertriglyceridemia. There are significant relationship of obesity (relative risk(RR)=18.7; 95% C.I 5.6–62.4; p=0.001), obesity and hypertrigliseridemia (RR=5.1; 95% C.I 2.7–9.5; p<0.001) with fatty liver. There are a significant relationship of fatty liver and as well as obesity. Triglyceride is not contributing directly to fatty liver but hypertriglyceridemia with obesity have significant relationship with fatty liver.
Authors and Affiliations
Syaharuddin Kasim, Mansur Arief, Agus Sulaeman, Joko Widodo
Keywords
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