RELATIONSHIP BETWEEN THE RETINAL NERVE FIBRE LAYER (RNFL) PARAMETERS AND VISUAL FIELD LOSS IN ESTABLISHED GLAUCOMA PATIENTS IN SOUTH INDIAN POPULATION
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2013, Vol 2, Issue 3
Abstract
Purpose: Optical coherence tomography (OCT) and Scanning LASER polarimetry (GDX-VCC) are newer techniques to analyse retinal nerve fibre loss in glaucoma. This study aims to evaluate the relationship between the Retinal Nerve Fibre Layer(RNFL) parameters measured using Stratus-OCT and GDx-VCC and visual field loss by Octopus interzeag perimetry in established glaucoma patients in South Indian Population. Materials and methods: Prospectively planned cross sectional study of 67 eyes of 34 established glaucoma patients on medical management. The mean age of patients was 46.911 years (SD+13.531). A complete ophthalmic examination, automated perimetry with octopus interzeag 1-2-3 perimeter, retinal nerve fibre analysis with GDx VCC and Stratus OCT was done. The differences between the mean RNFL parameters in the presence or absence of field defects were evaluated. Results: The data analysed were mean deviation, loss variance, OCT total average nerve fibre thickness, GDX VCC- TSNIT average and Nerve fibre indicator (NFI).The data were split into two subgroups on the basis of presence or absence of visual field defect and analysed. The difference between the mean value of NFI between the subgroups was highly significant with a p value < 0.01.The OCT parameter Total average nerve fiber layer thickness differed significantly between the two subgroups (p value <0.05). The mean GDx TSNIT average did not differ significantly between the two subgroups. Conclusion: The total average nerve fibre thickness by OCT correlated better with visual field loss than the GDX TSNIT average .Among the GDx parameters, the NFI was found to be a better indicator of visual field damage than the average thickness.
Authors and Affiliations
Elangovan Suma| Assistant Professor of Ophthalmology, Meenakshi Medical College and Research Institute, Enathur, Kanchipuram, Tamilnadu, India Corresponding author email: elangovansuma@hotmail.com, Puri K Sanjeev| Assistant Professor of Ophthalmology, Meenakshi Medical College and Research Institute, Enathur, Kanchipuram, Tamilnadu, India
Keywords
Related Articles
- EP ID EP11049
- DOI 10.5958/j.2319-5886.2.4.117
- Views 321
- Downloads 18
IODINE STATUS OF FEMALE STUDENTS IN UNIVERSITY OF MAIDUGURI BORNO STATE
Background: Urinary iodine concentration is a sensitive marker of current iodine intake and can reflect recent changes in iodine status. Although an individual urinary iodine concentration varies daily, or even within...
Relationship between Leadership Style and Personality Type in Three Levels of Nursing Managers in Iran-Esfahan Medical University Hospitals In 2015
Proper leadership style helps proper functioning of nurses who are the most frequent experts in hospitals and improves quality of their work. One of the important factors affecting nurses` performance is the behaviors o...
PREVALENCE, CHARACTERIZATION AND CLINICAL SIGNIFICANCE OF KLEBSIELLA PNEUMONIAE CARBAPENEMASE (KPC) PRODUCING KLEBSIELLA PNEUMONIAE
Background: Klebsiella peumoniae, a capsulated gram negative bacillus is responsible for causing life threatening infections in humans. Carbapenems are the drug of choice for serious infection caused by multidrug resist...
GENDER DIFFERENCES IN BODY MASS INDEX AND BLOOD PRESSURE AMONG NORMAL HEALTHY UNDERGRADUATE STUDENTS
Introduction: Obesity, measured by body mass index (BMI) is one of the morbid non-communicable diseases in the modern world. Worldwide reports have indicated a rise in the prevalence of obesity among adults. Generally...
STUDY OF SERUM MALONDIALDEHYDE, NITRIC OXIDE, VITAMIN E LEVELS IN PATIENTS WITH RHEUMATOID ARTHRITIS
Background: Rheumatoid arthritis (RA) is a chronic progressive autoimmune disorder characterized by symmetric erosive synovitis and sometimes shows multisystem involvement. The long-term outcome of the disease is chara...