Relationship of IL-1β in Apical Periodontitis: A Systematic Review
Journal Title: Journal of Dental Health and Oral Research - Year 2024, Vol 5, Issue 3
Abstract
Introduction: Apical periodontitis is an inflammatory process of the periradicular tissues, caused by infection and the presence of persistent microorganisms within the root canal system. When toxins released by microorganisms reach the periapex, innate and adaptive immune cells release significant amounts of various inflammatory mediators such as tumor necrosis factor, interleukin 6, interleukin 17, interferon gamma, interleukin 1 α and β, inducing periapical bone resorption. Objective: Determine the relationship between the expression interleukin 1β and the development of apical periodontitis. Materials and methods: A systematic search was conducted in four electronic databases, PubMed, EBSCO Host, ScienceDirect and Wiley Online Library. Articles published from January 1, 2017, to May 10, 2022, were searched. Results: 7 articles were included for the systematic review. Conclusion: IL-1β plays an important role in the development and progression of apical periodontitis.
Authors and Affiliations
Hugo Alejandro Bojórquez-Armenta1, Yarely Guadalupe Ramos-Herrera1, Sergio Manuel Salas-Pacheco1, Omar Alejandro Tremillo-Maldonado1, Alondra Rosso-Guerrero1, Nohé Vargas-Chávez1, Ronell Bologna-Molina1, Oscar Eduardo Almeda-Ojeda1*
Keywords
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- EP ID EP753277
- DOI https://doi.org/10.46889/JDHOR.2024.5311
- Views 28
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