Reliability of fine needle aspiration cytology in the evaluation of palpable breast lumps – An institutional based study
Journal Title: IP Archives of Cytology and Histopathology Research - Year 2017, Vol 2, Issue 2
Abstract
Introduction: Fine needle aspiration cytology (FNAC) is a simple, minimally invasive, rapid, cost effective outpatient based diagnostic procedure for palpable breast lumps. The aim of present study was to evaluate the diagnostic performance of FNAC in the diagnosis of breast lesions. Materials and Method: This is a retrospective study done in the Department of Pathology, All India Institute of Medical Sciences, Patna during the period of May 2014 to May 2017. It included all the patients who presented with breast lumps and in whom FNA was performed. Cytological diagnosis was compared with histopathological diagnosis. Results: A total of 698 patients presented with breast lumps in this retrospective study of 3 years whose cytological findings were studied. Histopathological confirmations were obtained in 270 cases out of 272 cases in which histocytopathological correlation were done. The age of patients in the present study varied from 12-85 years. Fibroadenoma was the commonest breast lesion (206 cases, 29.5%), followed by carcinoma breast (106 cases, 15.2%) and fibrocystic diseases (97 cases; 13.9%). Sensitivity and specificity of FNAC in breast lesions were 98.11% and 100% respectively, with 100% positive predictive value and 98.81% negative predictive value. Diagnostic accuracy of FNAC in the present study was found to be 99.26%. Conclusion: FNA is a highly reliable, cost effective, less traumatic, repeatable and simple diagnostic modality of breast lumps. When combined with physical examination and imaging studies (triple assessment), FNAC is a highly sensitive diagnostic tool and can reduce the need for open biopsy.
Authors and Affiliations
Punam Prasad Bhadani, Shuchi Smita, Iffat Jamal, Ruchi Sinha, Somak Majumdar
Keywords
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