Repeated bouts of eccentrically biased endurance exercise stimulate salivary IgA secretion rate
Journal Title: Biology of Sport - Year 2015, Vol 32, Issue 1
Abstract
To determine the salivary secretory immunoglobulin A (sIgA) response to repeated bouts of unaccustomed, downhill running (eccentrically biased) and examine potential protective immunological adaption from a repeated bout effect. Eleven active but untrained males (age: 19.7±0.4 years; VO[sub]2[/sub]peak: 47.8±3.6 ml · kg[sup]-1[/sup] · min[sup]-1[/sup]) performed two 60 min bouts (Run 1 and Run 2) of downhill running (-13.5% gradient), separated by 14 days, at a speed eliciting 75% of their VO2peak on a level grade. Saliva samples were collected before (baseline), immediately post exercise (IPE), and every hour for 12 h and every 24 h for 6 days after each run. Salivary sIgA concentration was measured and sIgA secretion rate was calculated. Results were analysed using repeated measures ANOVA (12 h period: 2x14; 24 h intervals: 2x7; p ≤ 0.05) with Tukey post-hoc tests where appropriate. Results are reported as means ± SE. There was a significant (p < 0.0001) interaction effect for sIgA secretion rate, IPE, with higher values after Run 2, as well as a significant (p < 0.01) time effect with elevated levels IPE and between 24 h and 144 h. There was a run effect (p < 0.0001), with the sIgA secretion rate significantly higher after Run 2. Repeated bouts of unaccustomed, eccentrically biased exercise induced alterations in the salivary sIgA secretion rate. This may serve as a protective mucosal adaptation to exercise-induced tissue damage.
Authors and Affiliations
Andrew McKune, Dorota Starzak, Stuart Semple
Keywords
Related Articles
- EP ID EP59231
- DOI -
- Views 110
- Downloads 0
Polimorfizm genu ACTN3 u osób trenujących różne dyscypliny sportowe
Czynnik genetyczny stanowi istotny komponent w warunkowaniu wydolności fizycznej. Analizowano asocjację polimorfizmu genu aktyniny-3 (ACTN3) z wydolnością fizyczną mierzoną maksymalnym poborem tlenu (VO2max).Badania prze...
Aerobic fitness of elite female and male wrestlers
Aim: The purpose of this study was to assess the aerobic fitness of elite female wrestlers, and to determine whether there are gender differences in the physiological response to graded exercise. Materials and Methods: T...
URINARY CREATINE AT REST AND AFTER REPEATED SPRINTS IN ATHLETES: A PILOT STUDY
Creatine plays a key role in muscle function and its evaluation is important in athletes. In this study, urinary creatine concentration was measured in order to highlight its possible significance in monitoring sprinters...
EXERCISE MYOPATHY: CHANGES IN MYOFIBRILS OF FAST-TWITCH MUSCLE FIBRES
The purpose of the present study was to determine the relationships between the changes of myofibrils in fast-twitch oxidative-glycolytic (type IIA) fibres and fast-twitch glycolytic (type IIB) muscle fibres, protein syn...
Age-related decrease of the indices of aerobic capacity in the former elite rowers and kayakers
Age-dependent changes of the indices of aerobic capacity were estimated in sixty-six former elite rowers and kayakers aged 30 to 67 years who were divided, according to their present recreational physical activity, into...