Report concerning the colaborative study for establish of reference standard eficacity of Kanamycin
Journal Title: Medicamentul Veterinar / Veterinary Drug - Year 2015, Vol 9, Issue 2
Abstract
The Microbiology Laboratory from the Institute for the Control of Veterinary Biological Products and Medicines participated to a collaborative study in order to determine the potency of kanamycin CRS, batch 3, according to the protocol sent by the EDQM (European Directorate for the Quality of Medicines) - coordinating of the study. The purpose of the study was to establish the potency of the batch 3 for in the characterization of the substance as reference standard. Potency was determined by microbiological method, based on comparison of the inhibition zones of growth of micro-organisms sensitive to those of a reference standard, as specified in European Pharmacopoeia, Chapter 2.7.2. - Microbiological testing of antibiotics. After analysis of received data from participants and their statistical processing by the EDQM, the potency of the batch 3, kanamycin reference materials, was established in 790 UI/mg.
Authors and Affiliations
Simona Sturzu, Daniela Tirsinoaga, Ioana Tihulca, Mariana Dumitrache, Alina Draghici, Cristina Popica, Valentina Nastase
Keywords
Related Articles
- EP ID EP95718
- DOI -
- Views 117
- Downloads 0
The efficacy of 30% FENBENDAZOLE anthelmintic paste in cyathostominosis in horses
Horse cyathostominosis is a large intestine helminthosis caused by parasites belonging to the family Strongylidae, subfamily Cyathostominae. The cyathostomins (small strongyles) represent a challenge for the parasitol...
Biochemical effect of Ginko biloba extract on carbohydrate metabolism in (induced type two) diabetic rats
Ginkgo biloba extract (EGb 761) has been used in traditional Chinese medicine for 5000 years that possesses various biological activities and has been shown to be useful in diabetes treatment. This study was carried...
Algorithm of calculation of Predicted No-effect Concentration (PNEC) for evaluation of the environmental risk of veterinary medicinal products
The environmental risk analysis for veterinary medicinal products is an assessment of their possible evolution, exposures, and effects and is structured according to the VICH GL6 (Phase I) and GL38 (Phase II) guides. The...
Report concerning the colaborative study for establish of reference standard eficacity of Rifamycin
The Microbiology Laboratory from the Institute for the Control of Veterinary Biological Products and Medicines participated in a collaborative study in order to determine the potency of rifamycin CRS, batch 4, according...
Instructiuni pentru Autori
No abstract