Report concerning the colaborative study for establish of reference standard eficacity of Teicoplanin
Journal Title: Medicamentul Veterinar / Veterinary Drug - Year 2015, Vol 9, Issue 2
Abstract
The Microbiology Laboratory from the Institute for the Control of Veterinary Biological Products and Medicines participated to a collaborative study in order to determine the potency of teicoplanin CRS, batch 2, according to the protocol sent by the EDQM (European Directorate for the Quality of Medicines) - coordinator of the study. The purpose of the study was to determine the potency of the batch 2 teicoplanin in the characterization of the substance as reference standard. Potency was determined by microbiological method, based on comparing the inhibition zones of growth of micro-organisms sensitive to those of a reference standard, as specified in European Pharmacopoeia, Chapter 2.7.2. - Microbiological testing of antibiotics. After analysis of received data from participants and their statistical processing by the EDQM, the potency of the batch 2, teicoplanin - reference materials, was established in 50150UI/fiola.
Authors and Affiliations
Simona Sturzu, Daniela Tirsinoaga, Ioana Tihulca, Mariana Dumitrache, Alina Draghici, Valentina Nastase
Keywords
Related Articles
- EP ID EP143517
- DOI -
- Views 81
- Downloads 0
Despre babesioza canină
Prezentul referat bibliografic, adresat medicilor veterinari clinicieni dar și celor din domeniul cercetării are ca scop rememorarea bolii din punct de vedere al etiologiei, al manifestărilor clinice și al managementului...
Simple and rapid method on High Performance Liquid Chromatography for simultaneous determination of benzylpenicillin potassium, streptomycin sulphate and related substances in Ascomicin – a veterinary use ointment
A new simple, rapid, accurate and precise High – Performance Liquid Chromatography (HPLC) method for determination of benzylpenicillin potassium and streptomycin sulphate in Ascomicin ointment was developed and validated...
Values for serotonin as an indicator for the dogs’ emotional state – Case study on eight dogs
The study was carried out on 8 mixt-breed dogs, ages 1-8 years old, which we took blood samples from in order to determine the serotonin content at four differnet moments. The first moment of blood sampling was registere...
About tablets and them use in veterinary medicine
This paper is a brief description of tablets and possible uses in veterinary therapeutics. Are described: classification, components, method of preparation and methods of compression defects and control tablets. Are also...
Algorithm of calculation of Predicted No-effect Concentration (PNEC) for evaluation of the environmental risk of veterinary medicinal products
The environmental risk analysis for veterinary medicinal products is an assessment of their possible evolution, exposures, and effects and is structured according to the VICH GL6 (Phase I) and GL38 (Phase II) guides. The...