The thyroid and the thyroid hormones
Journal Title: Medicamentul Veterinar / Veterinary Drug - Year 2014, Vol 8, Issue 2
Abstract
The thyroid gland is located in the cervical fascia were it is divided in two lateral lobes, right and left, disposed on both sides of the trachea, and unlike other vertebrates, the cat does not have an isthmus that connects the two lobes. The main products of secretion of the thyroid gland are represented by thyroxine [T4] and 3,5,3 'triiodothyronine [T3]. To these are added other hormones resulted from the deiodination of the principle hormones. This process is catalized by the D1, D2 and D3 deiodinase resulting 3,3,5' triiodothyronine [rT3], 3,5-T2, 3,3’-T2 or 3’,5’-T2 which by further deiodination will form 3-3'-T1 and T1. To reach this deiodination must be followed certain steps in the hormon synthesis transport path and it is important the present of the carrier protein. Once inside the tissue, the concentration of each hormone will vary depending on the binding site and the metabolic processes that will be followed.
Authors and Affiliations
Andreea Pap, Crina Mosneang, Romeo Cristina
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