Research progress on mitochondrial autophagy in sepsis-related acute lung injury
Journal Title: Perioperative Precision Medicine - Year 2025, Vol 3, Issue 1
Abstract
Sepsis is a systemic inflammatory response syndrome caused by infection, leading to acute lung injury and acute respiratory distress syndrome, which are common life-threatening complications in intensive care units. Mitochondrial autophagy, a process that selectively removes damaged mitochondria, is essential for maintaining the stability of the intracellular environment and cellular function. In recent years, the role of mitochondrial autophagy in sepsis-associated acute lung injury and acute respiratory distress syndrome has garnered significant attention. This review summarizes the research progress of mitochondrial autophagy in sepsis-associated acute lung injury and acute respiratory distress syndrome, focusing on its mechanism, influencing factors, and potential therapeutic agents.
Authors and Affiliations
Kecheng Zhai, Yangmengna Gao, Yu Xiang, Jiameng Liu, Shangping Fang
Keywords
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- EP ID EP765128
- DOI 10.61189/619896szhnms
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