Research Progress on Pharmacological and Toxicological Effects of Bavachin
Journal Title: Journal of Experimental and Clinical Application of Chinese Medicine - Year 2024, Vol 5, Issue 4
Abstract
Objective: To analyze and summarize the latest research progress regarding pharmacological and toxicological effects of bavachin. Methods: Through retrieval of all bavachin-related reports on pubmed, CNKI, Wanfang database and other databases, the pharmacologic and toxicological effects of bavachin were sorted out and concluded accordingly. Results: The study showed that bavachin had a wide range of pharmacological activities, including estrogen-like, anti-inflammatory, anti-tumor, immunoregulatory, anti-diabetes and its complications effects. The toxicological effects of bavachin were mainly manifested in three aspects: hepatotoxicity, reproductive toxicity and nephrotoxicity. Conclusion: Bavachin has the characteristics of multi-function and multi-target monomer similar to traditional Chinese medicine, and broad application prospects, but also has certain toxicological effects. How to avoid toxicity, as well as enhance strengths and avoid weaknesses is the direction of development and utilization of bavachin. This review provides reference for further development and utilization of bavachin.
Authors and Affiliations
Yeqing Jiang, Shiyu Hu, Jiaman Shen, Dongling Shi
Pharmacological Activities of a Chinese Herb, Glycine tomentella (I-Tiao-Gung): A Systematic Review
I-Tiao-Gung, Glycine temetella Hayata, has been used as a traditional herbal medicine for pain relief. This review provides science-based evidences that support the traditional concept. The 95 % ethanol extract of I-Tiao...
The Effects of Multiple Kidney-Tonifying Chinese Medicines on Thymus Regeneration in Rapamycin-Induced Mice
Background: Rapamycin is universally recognized as a potential anti-aging drug, the important functional activities of which involve induction of reversible acute atrophy of the thymus and normal regeneration after disco...
Effect of Jinhuahecha—A Fermented Green Tea on DSS-Induced Ulcerative Colitis in Mice and Its Preliminary Pharmacological Mechanism
Background: Ulcerative colitis (UC) is an inflammatory bowel disease. Jinhuahecha (JHHC)-a fermented green tea is obtained by micro-fermentation of Anji white tea (AJWT) inoculated with high-purity "E. cristatum". Purpos...
Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions
The complex syndrome of obesity is a complex syndrome associated with various metabolic disorders, poses significant threats to human health. Many weight loss medications have the potential to rapidly treat obesity, howe...
Research Progress on Pharmacological and Toxicological Effects of Bavachin
Objective: To analyze and summarize the latest research progress regarding pharmacological and toxicological effects of bavachin. Methods: Through retrieval of all bavachin-related reports on pubmed, CNKI, Wanfang databa...