Research progress on the CD4 +T cell balance in oral cancer and precancerous diseases
Journal Title: 口腔疾病防治 - Year 2019, Vol 27, Issue 2
Abstract
CD4 +T cells play an important role in regulating adaptive immune responses to various inflammatory responses. Parental T cell populations can differentiate in response to different cytokines into at least four subpopulations: Th1, Th2, Th17, and Treg cells. These differentiated T cells participate in various immune responses and have different roles and functions in oral cancer and precancerous diseases. The Th1/Th2 balance, the Th17/Treg balance and the occurrence and development of oral cancer and precancerous diseases are related to immune imbalances. Reversing these T cell imbalances and strengthening the patient’s autoimmune function may prevent or even reverse the progression of oral and precancerous diseases. This paper reviews the research advances on the CD4 +T cell balance in oral cancer and precancerous lesions.
Authors and Affiliations
TIAN Yuanye, TANG Zhangui
Keywords
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- EP ID EP663201
- DOI 10.12016/j.issn.2096-1456.2019.02.010
- Views 174
- Downloads 0
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