RESTRAIN OF FEAR: PARTICIPATION OF GABA NEUROTRANSMITTER SYSTEM
Journal Title: Problems of Psychology in the 21st Century - Year 2013, Vol 6, Issue 7
Abstract
In experiences on rats in the conditions of free behavior at development of a conditioned of passive avoidanсe reflex (the first series) and a defensive reflex and a conditional inhibition (the second series) it is revealed, and elaboration of internal inhibition and Phenibut – a nonspecific agonist of GAMKA and GAMKB receptors cause in experimental animals weakening of freezing arising in a dangerous situation, and a disinhibition of research behavior. Results of experiences in the accounting of data of the literature allow to assume that both factors, and elaboration of internal inhibition, and Phenibut weaken freezing – the phenomenon used in experiments as a biological analog of fear, owing to increase of level of activity of the GABA neurotransmitter system of a brain.
Authors and Affiliations
Shulgina, GI, Berezhnaya, DA, Parfentyev, NA
Keywords
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