RESULTS OF COCHLEAR IMPLANTATION IN CHILDREN WITH CONGENITAL CYTOMEGALOVIRUS INFECTION VERSUS GJB2 MUTATION
Journal Title: Journal of Hearing Science - Year 2015, Vol 5, Issue 2
Abstract
Background: Children with congenital cytomegalovirus (CMV) infection face a bigger risk of neurological deficits and developmental delays associated with sensorineural hearing loss (SNHL). Their rehabilitation with a cochlear implant (CI) may therefore be inferior to the paediatric population in general. This study describes post-implant outcomes in children with CMV-related deafness and compares them to children with genetic deafness caused by GJB2 mutation (connexin 26) rehabilitated at the Centro Hospitalar e Universitário de Coimbra, Portugal. Materials and methods: We conducted a revision of 11 children with profound hearing loss caused by congenital CMV infection rehabilitated with a CI in our institution. The children were divided into 3 groups according to age of implantation (<2 years, 2–3 years, >3 years) and their performance was compared to a group of children with genetic hearing loss caused by GJB2 mutation. To compare performance the following tests were applied: SIR, CAP, vocal characteristics evaluation grid (VCEG), MAIS, and MUSS. Results: We found no differences between the two groups in terms of hearing thresholds obtained with a CI. In spite of a wider spread of results in the CMV group, there were no significant statistical differences in the SIR and VCEG tests or in the MAIS and MUSS questionnaires. There was a significant difference in the CAP test (p=0.049) where the GJB2 group had superior results. Conclusions: The present study has shown that the CMV group had poorer results for the CAP test and a wider spread of results in the other tests. However, the CMV group attained results comparable to children with profound hearing loss and no other deficit, and benefited from rehabilitation with a cochlear implant.
Authors and Affiliations
Raquel Ferriera, Jorge Martins, Marisa Alves, Jose Oliveira, Luis Silva, Carlos Ribeiro, Antonio Paiva
Keywords
Related Articles
- EP ID EP169346
- DOI -
- Views 64
- Downloads 0
HEARING LOSS AND VERY LOW BIRTHWEIGHT
Background: Regardless of gestational age, any newborn (NB) with a weight at birth of <1500 g is considered to be of very low birth weight (VLBW). The incidence of hearing loss in this population group is 5–6% but the fr...
HIGH-FREQUENCY DISTORTION PRODUCT OTOACOUSTIC EMISSIONS MEASURED BY TWO SYSTEMS: AN EXAMPLE OF A SUBJECT WITH NORMAL HEARING
Background: Distortion product otoacoustic emissions (DPOAEs) are most commonly measured up to 6 kHz. However, there are now systems available that can measure DPOAEs up to 16 kHz. The purpose of this study was to compar...
POSTLINGUAL SENSORINEURAL HEARING LOSS DUE TO A VERY RARE COCH PATHOGENIC VARIANT
Background: The COCH gene encoding cochlin is highly expressed in the inner ear but the exact physiological function of the protein still remains unknown. Pathogenic variants located in COCH cause autosomal dominant hear...
THE 12TH EUROPEAN SYMPOSIUM ON PEDIATRIC COCHLEAR IMPLANTS (ESPCI), JUNE 18–21, 2015, TOULOUSE, FRANCE
The 12th European Symposium on Pediatric Cochlear Implants (ESPCI) was held in Toulouse, France on 18–21 June 2015. The first ESPCI was organized in 1992 in Nottingham and since then the growing interest in pediatric coc...
COEXISTENCE OF BILATERAL SULCUS VERGETURE AND BILATERAL FIBROUS MASS OF THE VOCAL FOLDS: CASE REPORT
Background: This study presents the case of a 32-year old woman who presented with severe dysphonia. She had experienced voice problems since childhood Materials and methods: The patient underwent otolaryngological and p...