Retinal Nerve Fiber Layer Thickness in a Subset of Karachi (Pakistan) Population
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 9
Abstract
Aim: To provide the normal range of retinal nerve fiber layer (RNFL) thickness in a subset of Karachi population by Spectralis OCT and to evaluate the effects of age and gender on it. Methodology: 300 eyes from 150 healthy subjects aged 40 years and above with no ocular pathologies were examined using standard protocols by a single examiner. Subjects with high myopia, history of diabetic or hypertensive retinopathy, raised intraocular pressure (> 21 mmHg) and previous intraocular or laser surgery were excluded from the study. The mean retinal nerve fiber layer thickness was calculated and was correlated with age and gender difference. Results: The mean global retinal nerve fiber layer thickness was found to be 99.02±9.08 μm in our set of population. Out of four quadrants the maximum RNFL thickness was found in inferior quadrant (126.45±16.23 μm) followed by the thickness of 121.50±15.03 μm in superior quadrant, 78.99±13.99 μm in nasal quadrant and 68.90±13.10 μm in temporal quadrant. We found strong negative correlation of RNFL thickness with age (P= 0.001) and not significant relation with gender (P= 0.8). Conclusions: Keeping in mind the variations in RNFL thickness with ethnic differences, this study provides the normal values of RNFL thickness according to our set of population. It is concluded that RNFL thickness decreases significantly with increasing age but gender had no significant effect on it.
Authors and Affiliations
Sahrish Mukhtar, Nuzhat Hassan, Zafar Dawood, Nosheen Zehra
Keywords
Related Articles
- EP ID EP348505
- DOI 10.9734/BJMMR/2015/20525
- Views 82
- Downloads 0
Knowledge, Awareness and Attitudes on Organ Donation among Undergraduate Medical Students in Malaysia: An Analytical Cross Sectional Study
There is a shortage of organs for transplant globally. Malaysia has one of the lowest deceased organ donation rates in the world. The shortage in organ supply is perceived to be due to a lack of awareness and knowledge a...
Formulated Composite Insoles Reduce Foot Pain and Fatigue and Increase Working Efficiency in Healthcare Workers: A Pilot Non-controlled Experimental Study
Aim: The aim was to evaluate self-assessed foot health status and working efficiency of healthcare workers when using composite insoles to treat foot problems. Introduction: Foot pain and fatigue are two of the most comm...
Assessment of Biochemical Changes in Pregnancy Induced Hypertension (PIH) among Saudi Population at KAMC-Riyadh
Background: One of the most common complications that affect around 2-5% pregnant women is elevated blood pressure defined as gestational hypertension. Aims & Objective: To compare and correlate between plasma urea, cre...
Demystifying the Mystified - An Ambiguous Presentation of Cemento-ossifying Fibroma in Maxilla
Cemento-ossifying fibroma is a slow growing benign tumor of mesenchymal origin. It is typically found in craniofacial bones, frequently involving the mandible and it tends to occur in third and fourth decade of life with...
Traditional Medicine and Modern Medicine: Knowledge, Attitude and Practice of Medical Students and Their Mothers in Tabuk City, Saudi Arabia
Background: Traditional remedies are mostly used as auto-medications for the treatment of physical diseases not only in Saudi Arabia but also worldwide. The traditional preparations are also prescribed by practitioners t...