Retrospective And Prospective Evaluation of Sloan Kettering Nomogram for Assessment of Axillary Lymph Node Involvement in Carcinoma Breast At Avbrh, Wardha
Journal Title: Journal of Medical and Dental Science Research (Quest Journals JMDSR) - Year 2017, Vol 4, Issue 8
Abstract
Bevilacqua et al have developed a nomogram to help estimate the risk of lymph node (LN) metastasis. The nomogram developed in the Memorial Sloan Kettering Cancer Center (MSKCC) is based on nine factors, which were found to be predictive: age, tumor size, tumor type, tumor location, lymphovascular invasion, mulifocality, histologic grade, estrogen receptor and progesterone receptor status. The area under the receiver–operator characteristic curve (AUC) was 0.771 in the validation data. This study evaluated the risk factors for LN metastasis and validated the value of the MSKCC nomogram for the prediction of LN metastasis Aim: To evaluate the axillary lymph node metastasis by MSKCC Nomogram at AVBRH. Objectives.1)To study the clinical staging of carcinoma breast .2) To evaluate the accuracy of MSKCC nomogram for axillary lymph nodes after axillary dissection (as standard form of treatment in MRM ). Materials And Methods:- All the patients with carcinoma breast with clinically N0 and N1 nodal status attending in the AVBRH of JNMC will be included in the study. Study was conducted retrospectively and prospectively for the evaluation of the MSKCC Nomogram. Type Of Study: observational study.Sample size:-100 cases 50 retrospective cases and 50 prospective Cases. Result :- In our present study as per the auc which is 0.771 validates mskcc nomogram at our setup with the point to be noted that the intermediate risk group needs to be looked for the size of tumour and lymphovascular invasion by a trucut biopsy method preoperatively to finally decide the fate of axillary lymph node dissection . Conclusion:- The MSKCC nomogram is a very useful tool in predicting the axillary LNodal metastasis in breast carcinoma patients who are in a N0 or N1 axillary lymph nodal state and might avoid an unnecessary axillary lymph nodal dissection at our setup decreasing the varied morbidity caused by it.
Authors and Affiliations
Dr Vivek Sharan Sinha
Keywords
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