REVIEW ON APPLICATION AND FACTOR AFFECTING AND OFFICIAL MONOGRAPHS IN DISSOLUTION PROCESS
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 3
Abstract
Dissolution testing is a critical methodology which is widely utilized in the development of a new pharmaceutical product. The test, in its simplest form, consists of placing the formulation in a dissolution apparatus containing suitable dissolution medium, allowing it to dissolve over a specified period of time and then assaying the resultant solution using appropriate analytical method to determine the amount of drug. Dissolution tests are relevant for an array of investigations like drug degradation profiles, stability and shelf life studies, physical and mechanical testing of dosage forms, incoming QC testing on raw materials etc. The present review outlines the recent findings on various dissolution apparatuses, their modifications, methods for degassing of media like Helium sparging, Heating and filtering, Vacuum degassing, sonication and dissolution testing of various dosage forms like Immediate Release (IR) Dosage forms, Delayed Release Dosage Forms, Extended Release Dosage Forms, Transdermal Delivery Systems, Powders, Chewable Tablets, Buccal Tablets, Chewing Gums, Soft Gelatin Capsule , Aerosols, Suppositories and other Semisolids.
Authors and Affiliations
Mohammad Zishan
Keywords
Related Articles
- EP ID EP295507
- DOI 10.22270/jddt.v7i3.1422
- Views 78
- Downloads 0
STUDIES ON ENDOPHYTES AND ANTIBACTERIAL ACTIVITY OF SAUSSUREA COSTUS (FALC.)
Different plant parts (root, stem, leaf) of Saussurea costus were used to isolate and investigate endophytic fungal species in summer, rainy and winter seasons. Total ten species of endophytic fungi belonging to seven ge...
DEVELOPMENT OF MUCOADHESIVE MICROSPHERES OF LEVOFLOXACIN FOR THE TREATMENT OF H. PYLORI INFECTION
The rationale of the present investigation is to develop a new oral drug delivery system utilizing both the concepts of controlled release and mucoadhesiveness, which could remain in stomach and control the drug release...
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEMS OF GLIPIZIDE FOR THE MANAGEMENT OF TYPE-II DIABETES MELLITUS
The objective of the present study was to fabricate and evaluate a chronomodulated pulsatile drug delivery system to maintain the blood glucose level by releasing the drug at a predetermined time interval. The basic desi...
Formulation and evaluation of orodispersible tablets of lornoxicam
Orodispersible tablets (ODTs), also known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in the mouth in seconds without chewing and the need of water. The purpose of this inves...
EFFECT OF ETHANOLIC EXTRACTS OF ABUTILON INDICUM, ZEA MAYS AND COMBINATION ON CALCIUM OXALATE UROLITHIASIS IN RAT
In the present study the effect of calcium oxalate urolithiasis urinary risk factor of ethanolic extract of Abutilon indicum, Zea mays and their combination have been studied in albino rats. From this study it is deduced...