REVIEW ON APPLICATION AND FACTOR AFFECTING AND OFFICIAL MONOGRAPHS IN DISSOLUTION PROCESS
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 3
Abstract
Dissolution testing is a critical methodology which is widely utilized in the development of a new pharmaceutical product. The test, in its simplest form, consists of placing the formulation in a dissolution apparatus containing suitable dissolution medium, allowing it to dissolve over a specified period of time and then assaying the resultant solution using appropriate analytical method to determine the amount of drug. Dissolution tests are relevant for an array of investigations like drug degradation profiles, stability and shelf life studies, physical and mechanical testing of dosage forms, incoming QC testing on raw materials etc. The present review outlines the recent findings on various dissolution apparatuses, their modifications, methods for degassing of media like Helium sparging, Heating and filtering, Vacuum degassing, sonication and dissolution testing of various dosage forms like Immediate Release (IR) Dosage forms, Delayed Release Dosage Forms, Extended Release Dosage Forms, Transdermal Delivery Systems, Powders, Chewable Tablets, Buccal Tablets, Chewing Gums, Soft Gelatin Capsule , Aerosols, Suppositories and other Semisolids.
Authors and Affiliations
Mohammad Zishan
Keywords
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- EP ID EP295507
- DOI 10.22270/jddt.v7i3.1422
- Views 99
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