REVIEW ON METHOD DEVELOPMENT BY HPLC
Journal Title: Int J of Pharm Rev& Res - Year 2014, Vol 4, Issue 4
Abstract
High-pressure or high-performance, liquid chromatography (both are abbreviated as HPLC or simply LC is predominantly used in the pharmaceutical industry for evaluations of a large variety of samples. It is the method of choice for checking purity of new chemical entities, monitoring changes. In synthetic procedures or scale up, evaluating new formulations, and carrying out quality control/assurance of the final drug product. It is important to pay special attention to the Develop methods that would resolve unknown potential impurities and degradation products, Develop strategies for instrument qualification and validation to meet regulatory requirements and Provides stringent validation of HPLC methods before they are utilized routinely
Authors and Affiliations
Balammal G1* , Saravana Kumar A2
Keywords
Related Articles
- EP ID EP111952
- DOI -
- Views 144
- Downloads 0
ANTIBIOTIC UTILIZATION IN ACUTE EXACERBATION OF ASTHMA AND COPD
One of the most common reasons why patients are presented to the emergency departments or primary care physicians is due to exacerbation of their asthma or COPD symptoms. Excessive use of antibiotics has been a growing c...
FORMULATION AND EVALUATION OF ZOLPIDEM TARTRATE SUBLINGUAL TABLETS
In the present study 3.5 mg strength will be going to be prepared and also evaluated for all the physical parameters evaluation and in-vitro drug dissolution studies. The first strategy was developed based on innovator c...
SCREENING OF PHYTOCHEMICAL CONSTITUENTS FROM CERTAIN FLOWER EXTRACTS
Extracts were prepared by adding 50 g of fresh flowers of Dillenia pentagyna Roxb., Garcinia gummigutta L., Hamelia patens Jacq., Hyptis suaveolens (L.) Poit., Ipomea tricolor Cav., Ixora coccinea L., Ochna obtusata DC.,...
DRUG TARGETING: BASIC CONCEPTS AND NANOSYSTEMS IN DRUG TARGETING
At present about 95% of all new potential therapeutic have poor pharmacokinetic and pharmacodynamics property. Either they get destroyed before going to systemic circulation or they get poorly absorbed. Hence, there is n...
FORMULATION DEVELOPMENT AND IN-VITRO EVALUATION OF CHRONOTHERAPEUTIC DRUG DELIVERY OF ROSUVASTATIN BY COMPRESSED COATED TECHNIQUE
Rosuvastatin is an HMG –COA reductase inhibitor, primarily used for the treatment of hyper cholestremia associated with cardiovascular diseases. It belongs to BCS class II having a half-life of 19 hrs and 20% bioavailabi...