REVIEW ON NANO EMULSION BASED DRUG DELIVERY SYSTEM
Journal Title: Asian Journal of Pharmaceutical Education and Research - Year 2018, Vol 7, Issue 2
Abstract
The most emerging branch in pharmaceutical sciences known as “Pharmaceutical nanotechnology” presents new tools, opportunities and scope, which are expected to have significant applications in disease diagnostics and therapeutics. Recently nano-pharamceuticals reveal enormous potential in drug delivery as carrier for spatial and temporal delivery of bioactive and diagnostics. Nanotechnology, shortened to nanotech, is the study of the controlling of matter on an atomic and molecular scale. Nanoemulsions (also referred as miniemulsions, submicron emulsions, ultrafine emulsions, finedispersed emulsions and so forth) are a group of dispersed particles used as vehicles for pharmaceutical aims and seem to be promising for the future of cosmetics, diagnosis, drug therapies and biotechnologies. Nanoemulsions are transparent or translucent dispersions, having the droplet size of less than 100 nm (the same droplet length-scale as microemulsions) with ultra low interfacial tension, large o/w interfacial areas and long-term physical stability. Literature review reveals that nanoemulsions containing solubilized drugs have been studied extensively as nanocarriers for the treatment of various diseases. Antibiotics, anticonvulsants and antihypertensives are among the drugs solubilized in nanoemulsions. The present review outlines the advantages and disadvantages of nanoemulsion with its preparation methods and therapeutic applications of nano-emulsion based drug delivery system of drugs published over the past decade.
Authors and Affiliations
Swati Patel, Grijesh Pandey, S. K. Yadav
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Poorly soluble drugs represent a problem for their scarce availability related to their low dissolution rate. The major drawback of low aqueous solubility is delays its absorption from the gastrointestinal tract.Solubili...
ANTIOXIDANT ACTIVITY OF SEED EXTRACT OF PSORALEA CORYLIFOLIA LINN.
The present study aimed to characterize the hydroalcoholic extracts prepared from seed of Psoralea corylifolia linn. The antioxidant potential of extract was evaluated using DPPH in vitro antioxidant models. This study,...
ANTI-ANEMIC ACTIVITY OF HYDRO-ALCOHOLIC LEAF EXTRACT OF BRASSICA OLERACEA VAR IN PHENYLHYDRAZINE INDUCED ANEMIC RATS
The study deals with the evaluation of anti-anemic activity of oral administration of hydro-alcoholic extract of fruit of Brassica oleracea at different dosage levels (250 & 500mg/kg body weight) on female Wistar rats us...
A COMPREHENSIVE REVIEW ON PHARMACOLOGICAL ACTIVITY OF VERNONIA ANTHELMINTICA AND CORALLOCARPUS EPIGAEUS
Medicinal plants have played an essential role in the development of human culture. Medicinal plants have been used in virtually all cultures as a source of medicine. Assurance of the safety, quality, and efficacy of med...
DEVELOPMENT AND EVALUATION OF TOPICAL LIPOSOMAL GEL LOADED WITH TAZAROTENE IN COMBINATION WITH HYDROQUINONE
The aim of the present study was to statistically optimize the vesicular formulations (Liposomes) for enhanced skin delivery of a model drug tazarotene in combination with gel contains hydroquinone. Regular 23 factorial...