Rhabdomyolysis after suicide attempt with escitalopram and enalapril
Journal Title: Ege Tıp Dergisi - Year 2017, Vol 56, Issue 3
Abstract
Rhabdomyolysis is a clinical syndrome characterized by muscle necrosis and the release of intracellular muscle ingredients into the blood circulation. The most serious complication is acute kidney injury. Rhabdomyolysis may occur due to various etiological factors. The most common reasons are crush injuries to muscle, excessive exercise, inflammatory muscle diseases, prolonged immobility, electrolyte imbalances and drug toxicity. The clinicians should be aware for rhabdomyolysis and its possible complications in drug poisoning cases. Enalapril may cause electrolyte imbalance and escitalopram may cause serotonin syndrome resulting rhabdomyolysis. In this paper we present a previously healthy fifteen years old girl, who developed rhabdomyolysis without electrolyte imbalance or neuroleptic syndrome after intake of enalapril and escitalopram for suicide attempt. A large number of drugs can cause rhabdomyolysis by different mechanisms. It should be kept in mind that the some drugs can cause rhabdomyolysis without causing significant clinical changes.
Authors and Affiliations
Sinan Oğuz, Nilden Tuygun, Can Demir Karacan
Keywords
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- EP ID EP336044
- DOI 10.19161/etd.393483
- Views 137
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