RHEUMATOID ARTHRITIS : AN UNDERSTANDING IN THE LIGHT OF HERBAL MEDICINES
Journal Title: Era's Journal of Medical Research - Year 2018, Vol 5, Issue 1
Abstract
Rheumatoid arthritis (RA) is characterised by chronic polyarticular synovial inflammation and progressive erosion of cartilage and bone. The disease occurs at any age, but is common among those aged between 40-70 years. RA has a worldwide distribution with prevalence of 1 to 2%. Pathogenesis of RA remains a mystery for past 40 years. Genetic studies established that people who carry specific MHC haplotypes show a higher risk for RA. Cytokines have also been implicated as important mediators of disease. Analysis of cytokine mRNA and protein in RA tissue revealed that TNF-, IL-1, IL-6, GM-CSF, and IL-8 are abundant. Reactive oxygen species (ROS) and Reactive nitrogen species (RNS) influences the inflammatory molecules. Antioxidants (exogenous or endogenous) are the compounds which prevent the generation of toxic oxidants. Treatment choice of the physician for RAis Non steroidal anti-inflammatory drugs (NSAIDs) and Disease modifying anti-rheumatic drugs (DMARDs). Herbal medicine is one of the oldest and traditional medicine systems around the world. Herbal products may contain a single herb or combinations of different herbs believed to have complementary effects. These contain potent bioactive substances.
Authors and Affiliations
Brijesh Rathore
Keywords
Related Articles
- EP ID EP407334
- DOI 10.24041/ejmr2018.62
- Views 153
- Downloads 0
CANCER CELL VIABILITY AND SURVIVAL IN VITRO AS FUNCTION OF CELL SURFACE ELECTRIC CHARGE: AN ANALYTICAL STUDY
Electrical charge is an indicator of the cellular state of health. In cells, the cell membrane is a leaky dielectric. Capacitors are composed of two conducting sheets separated by a thin layer of insulating material know...
OBSESSIVE COMPULSIVE SYMPTOMS IN PATIENTS WITH EPILEPSY
Obsessive Compulsive Symptoms in Patients with Epilepsy. To find out the prevalence of obsessive compulsive symptoms / disorder among patients of epilepsy. Patients with epilepsy diagnosed clinically at psychiatric out p...
bHCG FOR SCREENING OF GESTATIONAL HYPERTENSION : A PROSPECTIVE OBSERVATIONAL STUDY IN NORTH INDIAN POPULATION
To measure maternal serum beta human chorionic gonadotropin during 13-24 weeks of pregnancy and compare the same between those who develop pregnancy induced hypertension with those who do not. In a prospective study βhCG...
LAPAROSCOPIC MANAGEMENT OF PANCREATIC PSEUDOCYSTS :A NOVEL TECHNIQUE USING TITANIUM CLIPS OUR EXPERIENCE
Pseudocysts of pancreas is collection of fluid in the lesser sac enclosed by a wall of fibrous or granulation tissue as a consequence of acute pancreatitis, pancreatic trauma or chronic pancreatitis. Invasive drainage pr...
THE SECOND BRAIN
The ability of the microbiota of the gut to communicate with the brain and influence behaviour is an emerging topic of research.The enteric microbiota interacts with the host to form a relationship that governs homeostas...