“Rippled” Pattern Sebaceoma: Case Report
Journal Title: Meandros Medical and Dental Journal - Year 2017, Vol 18, Issue 3
Abstract
Sebaceoma is a benign neoplasm that originally defined by Troy and Ackerman. It is composed of sebaceous duct-like or cyst-like structures that contain clusters of mature sebaceous cells admixed with basaloid cells. Stroma is eosinophilic and sclerotic. They are most commonly seen in women and decades between 6 and 9, often on the face and scalp. Rippled patern sebaceoma is a recently designated histopathological variant of sebaceoma and a rare subtype. It is characterized by a dermal aggregation of monomorphous, small, basaloid sebaceous germinative cells. The stroma reminds of Verocay bodies. In our case, the patient applied to our hospital with complaints non-healing wound at scalp for 2 years. Material was sent for pathological assessment, and macroscopically has a nodular lesion. Under microscopic assessment, tumor that was localized in the dermis and sharply demarcated from the surrounding tissue was consisting fine granular, hyperchromatic nuclei, basaloid, round or slightly prolonged cells with eosinophilic cytoplasm. Necrosis, atypical mitoses or pleomorphism were not detected. Vacuolated cytoplasmic sebaceous differentiation cells were found scattered. There was formation of cigar-shaped basaloid cells as linear parallel cords in some areas. Cystic epithelium lining the lumina was stained with cytokeratin-19 and cytokeratin-8. Some of vacuolated cells were stained with cytokeratin-19. No staining with cytokeratin-7, S100 and epithelial membrane antigen was observed. Diagnosis of rippled patern sebaceoma was made with these histopathological findings.
Authors and Affiliations
Sevilay Gürcan, Canten Tataroğlu, Özlem Erdal Özdemir, Tuğba Özbek, Ayşe Gül Örmeci, Saime İrkören
Keywords
Related Articles
- EP ID EP236197
- DOI 10.4274/meandros.1756
- Views 148
- Downloads 0
Bilateral Incomplete Atypical Femoral Fracture due to Long-Term Bisphosphonate Use: A Case Report
Although the overall safety profile of bisphosphonates (BP) is favorable, adverse effects associated with long-term use have came up during recent years. In this report, a case of bilateral incomplete atypical femoral fr...
Vitamin D Level and Infertility
Infertility is one of the major health problems of our time. In fact, infertility is caused by many factors. Among these factors the effect of vitamin D levels of infertility are overlooked. The prevalence of vitamin D d...
A Comparison of Chewing Movements of Individuals with Normal Occlusion by the Patients with Orthodontic Abnormalities During Treatment Progress
Objective: Comparison of chewing movements of individuals with normal occlusion and those with orthodontic anomalies under treatment. Materials and Methods: This is a prospective clinical study carried out on a total of...
The Hemostatic Effect of Ankaferd Blood Stopper in Rat Bleeding Models with Antithrombotic Drug Therapy: An Experimental In Vivo Study
Objective: Ankaferd blood stopper is a mixture of five medicinal plant extracts used as a hemostatic agent for management of external hemorrhage. The aim of this study was to evaluate the hemostatic effects of Ankaferd b...
Protective Effect of Pycnogenol® on Cisplatin Induced-Cardiotoxicity in Rats
Objective: This study investigated the cardiotoxicity of cisplatin (CIS) on rat heart by using the oxidative damage of the rat myocardium, troponin I and serum S100A1 levels. Previous studies have reported that cell-prot...